Micoral 2% w/w (Oral Gel)
15 gm tube: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Miconazole nitrate |
| Company | Aci limited |
| Also available as |
Title, Categories, and Description
- Micoral Oral Gel
- Oral and gastrointestinal candidiasis treatment
- Antifungal and antibacterial medication
- Aural Anti-fungal preparations
Indications
- Treatment of oral and gastrointestinal candidiasis
- Eradication of fungal colonization
- Treatment of super infections due to gram-positive bacteria
- Treatment of dermatomycoses such as tinea pedis, tinea corporis, and tinea manuum
Pharmacology
- Antifungal activity against common dermatophytes and yeasts
- Antibacterial activity against certain gram-positive bacilli and cocci
- Inhibition of demethylation step in ergosterol biosynthesis
Pharmacokinetics
- Low oral bioavailability (25-30%)
- Systemic absorption after administration as oral gel
- Metabolized and excreted unchanged in urine
- Plasma half-life of 20-25 hours
Dosage
- Dosage guidelines for infants, children, and adults
- Different dosages for oropharyngeal and gastrointestinal tract candidosis
- Application frequency and missed dose instructions for oral gel and cream
Administration
- Application instructions for localized lesions of the mouth
- Recommendation to keep the gel in contact with the affected area for optimal results
- Guidance for oral candidosis and dental prosthesis
Interaction
- Avoidance of concomitant treatment with specific medications
- Potential for delaying metabolism of Phenytoin and Cyclosporine
Contraindications
- Contraindicated in patients with known hypersensitivity to the active ingredient
Side Effects
- Occasional nausea and vomiting
- Diarrhea with long-term use
- Rare allergic reactions
Pregnancy & Lactation
- No safety information during pregnancy
- Caution in nursing women due to potential excretion in human milk
Precautions & Warnings
- Monitoring anti-coagulant effect if used concomitantly
- Caution in infants and young children to prevent throat obstruction
Overdose Effects
- Potential for vomiting and diarrhea with accidental overdosage
- Symptomatic and supportive treatment for overdose
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children