Myco OG 2% w/w (Oral Gel)

15 gm tube: ৳ 55.00

Medicine Details

Category Details
Generic Miconazole nitrate
Company Pharmasia limited

Title

  • Myco OG Oral Gel

Categories

  • Oral Medication
  • Antifungal Medication
  • Topical Medication

Description

  • Myco OG oral gel is indicated for the treatment of oral and gastrointestinal candidiasis, eradication of fungal colonization in the mouth and gastrointestinal tract, treatment of super infections due to gram-positive bacteria, and indicated in dermatomycoses such as Tinea pedis, Tinea corporis, Tinea manuum, Candidial infections, and more.
  • Miconazole possesses antifungal activity against common dermatophytes and yeasts, as well as antibacterial activity against certain gram-positive bacilli and cocci. Its activity is based on the inhibition of a demethylation step in the ergosterol biosynthesis.

Dimensions

N/A

Color options

N/A

Functions

  • Treats oral and gastrointestinal candidiasis
  • Eradicates fungal colonization in the mouth and gastrointestinal tract
  • Treats super infections due to gram-positive bacteria
  • Rapidly alleviates symptoms such as pruritis
  • Treats dermatomycoses such as Tinea pedis and Tinea corporis

Materials

N/A

Technical specifications

  • Pharmacodynamics: Miconazole inhibits a demethylation step in the ergosterol biosynthesis, disrupting fungal cell membranes
  • Pharmacokinetics:
    • Oral bioavailability: Low (25-30%) due to little absorption from the intestinal tract
    • Plasma protein binding: 88.2%
    • Metabolism: Largely metabolized after absorption
  • Dosage:
    • Oral gel infants: 1.25 ml (1/4 measuring spoon) applied 4 times a day for infants 4-24 months
    • Oral gel adults children: 2.5 ml (1/2 measuring spoon) applied 4 times a day for adults and children 2 years of age and older
    • Cream application frequency: Twice daily for affected areas such as tinea pedis, tinea cruris, tinea corporis, and cutaneous candidiasis

Design elements

N/A

Usability features

  • Administration: Apply to affected area 2-4 times a day for localized lesions of the mouth, keep in contact with the affected area as long as possible
  • Missed dose: Apply missed dose as soon as remembered; in case of next dosing time, omit the missed dose and continue usual course

Interaction

  • Terfenadine astemizole cisapride: Should be avoided due to potential inhibition of metabolism
  • Phenytoin cyclosporine: May delay metabolism, monitor plasma levels when used concomitantly

Contraindications

Known hypersensitivity to the active ingredient

Side effects

  • Occasional nausea and vomiting
  • Diarrhea with long-term use
  • Rarely, allergic reactions

Pregnancy lactation

Avoid in pregnant women if possible; caution when administered to nursing women

Precautions warnings

  • Anticoagulant use: Monitor anti-coagulant effect when used concomitantly
  • Infants young children: Caution to ensure the gel does not obstruct the throat

Overdose effects

  • Effects:
    • Vomiting
    • Diarrhea
  • Treatment: Symptomatic and supportive

Storage conditions

Keep in a dry place away from light and heat; keep out of the reach of children

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