Miconex 2% w/w (Cream)

10 gm tube: ৳ 39.00

Medicine Details

Category Details
Generic Miconazole nitrate
Company Aci limited
Also available as

Indications

  • Treatment of oral candidiasis
  • Treatment of gastrointestinal candidiasis
  • Eradication of fungal colonization in the mouth and gastrointestinal tract
  • Treatment of super infections due to gram-positive bacteria
  • Treatment of dermatomycoses like Tinea pedis (Athlete's foot), Tinea corporis (Tinea circinata), Tinea cruris, Candidial infections, Tinea versicolor, Infections of the skin, Perianal infections, Stomatitis angularis (cheilitis), Balanoposthitis, Otitis externa
  • Rapid alleviating effect on pruritus

Pharmacology

  • Antifungal activity against common dermatophytes and yeasts
  • Antibacterial activity against certain gram-positive bacilli and cocci
  • Inhibition of demethylation step in ergosterol biosynthesis
  • Disruption in production of ergosterol leading to membrane disruption in fungal cells

Dosage

  • Miconazole Oral Gel dosage for oropharyngeal candidosis in infants, adults, and children
  • Miconazole Oral Gel dosage for gastrointestinal tract candidosis in infants, children, and adults
  • Miconazole Cream dosage for tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis, and tinea versicolor

Administration

  • Application 2-4 times a day directly to the affected area with a clean finger
  • Continued treatment for at least a week after symptoms have disappeared
  • Removal of dental prosthesis at night for oral candidosis

Interaction

  • Avoid concomitant treatment with Terfenadine, Astemizole, and Cisapride
  • Potential delay in Phenytoin and Cyclosporine metabolism

Contraindications

  • Not to be used in patients with known hypersensitivity to the active ingredient

Side Effects

  • Occasional nausea and vomiting
  • Diarrhea with long-term use
  • Rare allergic reactions

Pregnancy & Lactation

  • Avoid in pregnant women if possible
  • Caution in nursing women

Precautions & Warnings

  • Monitoring of anti-coagulant effect if used concomitantly
  • Monitoring of phenytoin plasma level if used concomitantly
  • Caution in infants and young children to avoid throat obstruction

Overdose Effects

  • Accidental overdosage may cause vomiting and diarrhea
  • Symptomatic and supportive treatment for overdose

Therapeutic Class

  • Aural Anti-fungal preparations

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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