Topicazole 2% w/w (Cream)
10 gm tube: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Miconazole nitrate |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of oral and gastrointestinal candidiasis
- Eradication of fungal colonization in the mouth and gastrointestinal tract
- Treatment of super infections due to gram-positive bacteria
- Treatment of dermatomycoses like Tinea pedis, Tinea corporis, Tinea manuum, etc.
- Treatment of candidial infections
- Treatment of infections of the skin (e.g. intertrigo)
- Treatment of perianal infections
- Treatment of stomatitis angularis (cheilitis)
- Treatment of balanoposthitis
- Treatment of otitis externa
Pharmacology
- Antifungal activity against common dermatophytes and yeasts
- Antibacterial activity against certain gram-positive bacilli and cocci
- Inhibition of demethylation step in ergosterol biosynthesis
- Disruption in production of ergosterol leading to fungal cell membrane damage
Dosage
- Dosage for oropharyngeal candidosis in infants and adults
- Dosage for gastrointestinal tract candidosis in infants, children, and adults
- Application instructions for miconazole cream for different skin conditions
- Information on missed dose and continuation of treatment
Administration
- Application frequency and method for localized lesions of the mouth
- Instructions for use with dental prosthesis for oral candidosis
- Duration of treatment after symptoms have disappeared
Interaction
- Avoidance of concomitant treatment with Terfenadine, Astemizole, and Cisapride
- Potential delay of Phenytoin and Cyclosporine metabolism
Contraindications
- Contraindication in patients with known hypersensitivity to the active ingredient
Side Effects
- Occasional nausea and vomiting
- Diarrhea with long term use
- Rare allergic reactions
Pregnancy & Lactation
- No information regarding the safety of Miconazole oral gel during pregnancy
- Caution advised when administered to a nursing woman
Precautions & Warnings
- Monitoring of anticoagulant effect when used concomitantly
- Caution in infants and young children to prevent throat obstruction
Overdose Effects
- Accidental overdosage may cause vomiting and diarrhea
- Symptomatic and supportive treatment required
Therapeutic Class
- Aural Anti-fungal preparations
Storage Conditions
- Storage in a dry place away from light and heat
- Keep out of the reach of children