Unigal 2% w/w (Cream)
15 gm tube: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Miconazole nitrate |
| Company | Opsonin pharma ltd |
| Also available as |
Title, Categories and Description
- Miconazole Oral Gel
- Aural Anti-fungal Preparations
- Oral and Gastrointestinal Candidiasis Treatment
- Dermatomycoses Treatment
- Antifungal and Antibacterial Activity
- Treatment of Super Infections due to Gram-Positive Bacteria
Dimensions
N/A
Color Options
N/A
Functions
- Treatment of oral and gastrointestinal candidiasis
- Eradication of fungal colonization
- Rapid alleviating effect on pruritis
- Treatment of tinea pedis, tinea corporis, tinea manuum, tinea cruris, candidial infections, tinea versicolor, skin infections, perianal infections, stomatitis angularis, balanoposthitis, otitis externa
Materials
- Miconazole
Technical Specifications
- Antifungal activity against common dermatophytes and yeasts
- Antibacterial activity against certain gram-positive bacilli and cocci
- Inhibition of demethylation step in ergosterol biosynthesis
- Low oral bioavailability (25-30%)
- Systemic absorption after administration
- Plasma protein binding (88.2%)
- Metabolized in the body
- Elimination half-life of 20-25 hours
Design Elements
N/A
Usability Features
- Applicable to infants, adults, and children 2 years of age and older
- Ease of administration for patients with difficulty swallowing tablets
Indications
- Treatment of oral and gastrointestinal candidiasis
- Eradication of fungal colonization in the mouth and gastrointestinal tract
- Treatment of super infections due to gram-positive bacteria
- Treatment of dermatomycoses including tinea pedis, tinea corporis, tinea manuum, tinea cruris, candidial infections, tinea versicolor, skin infections, perianal infections, stomatitis angularis, balanoposthitis, otitis externa
Mode of Action
- Antifungal activity against dermatophytes and yeasts
- Antibacterial activity against certain gram-positive bacilli and cocci
- Inhibition of ergosterol biosynthesis leading to disruption of fungal cell membrane
- Leakage of essential constituents from fungal cells resulting in cell death
Dosage
- Specific dosages for infants, adults, and children 2 years of age and older
- Instructions for missed dose
- Application guidelines for Miconazole Cream
- Duration of treatment for different conditions
Administration
- Application instructions for localized lesions of the mouth
- Recommendation for continued treatment even after symptoms disappear
- Removal and cleaning instructions for oral candidosis with dental prosthesis
Interaction
- Contraindication with Terfenadine, Astemizole, and Cisapride
- Potential delay of Phenytoin and Cyclosporine metabolism
Contraindications
- Known hypersensitivity to Miconazole
Side Effects
- Occasional nausea and vomiting
- Diarrhea with long term use
- Rare allergic reactions
Pregnancy & Lactation
- No available information on safety during pregnancy
- Caution advised for nursing women
Precautions & Warnings
- Monitoring of anticoagulant effect if used concomitantly
- Monitoring of phenytoin plasma levels in concomitant use
- Caution in infants and young children to prevent throat obstruction
Overdose Effects
- Accidental overdosage may cause vomiting and diarrhea
- Symptomatic and supportive treatment recommended
- Specific antidote not available
Therapeutic Class
- Aural Anti-fungal Preparations
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children