Infud 250 mg (Tablet)

Unit Price: ৳ 50.00 (3 x 4: ৳ 600.00)
Strip Price: ৳ 200.00

Medicine Details

Category Details
Generic Terbinafine hydrochloride
Company General pharmaceuticals ltd
Also available as

Indications

  • Treatment of onychomycosis
  • Tinea Capitis
  • Fungal infection of the skin
  • Pityriasis versicolor

Pharmacology

Inhibition of Ergosterol biosynthesis, Fungicidal activity, Active against Tricophyton Mentagrophyte and Trichophyton Rubrum

Dosage & Administration

  • Terbinafine tablet:
    • Treatment for fingernail onychomycosis
    • Treatment for toenail onychomycosis
  • Terbinafine granules: Dosage based on body weight
  • Terbinafine cream:
    • Application once or twice daily
    • Duration of treatment varies by infection type
  • Terbinafine 1% Spray: Applied once or twice daily, duration varies by indication

Interaction

Inhibitor of CYP450 2D6 isozyme, Potential interactions with specific drug classes

Contraindications

Contra-indicated in individuals hypersensitive to terbinafine

Side Effects

  • Gastrointestinal symptoms
  • Liver test abnormalities
  • Rashes
  • Urticaria
  • Pruritus
  • Taste disturbances
  • Idiosyncratic and symptomatic hepatic injury
  • Serious skin reactions
  • Severe neutropenia
  • Thrombocytopenia
  • Angioedema
  • Allergic reactions
  • Malaise
  • Fatigue
  • Vomiting
  • Arthralgia
  • Myalgia
  • Hair loss

Pregnancy & Lactation

  • Terbinafine tablet: Not recommended during pregnancy or nursing
  • Terbinafine cream: Should not be administered unless benefits outweigh potential risks

Precautions & Warnings

  • Warnings:
    • Rare cases of liver failure
    • Serious skin reaction
  • Precautions:
    • Not recommended for patients with chronic or active liver disease
    • Assessment of pre-existing liver disease before prescribing

Use in Special Populations

  • Pediatric use: Safety and efficacy not established
  • Use in the elderly: No evidence for different dosages or side-effects

Overdose Effects

Limited clinical experience, Symptoms include nausea, vomiting, abdominal pain, dizziness, rash, frequent urination, headache

Therapeutic Class

  • Other Antifungal preparations
  • Topical Antifungal preparations

Storage Conditions

Store in a cool and dry place, below 30°C, protect from light

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