Mycofin 1% (Cream)
5 gm tube: ৳ 50.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Title
- Mycofin Tablet
- Mycofin Granules
- Mycofin Cream
- Mycofin 1% Spray
Categories
- Antifungal Medicine
- Oral Antifungal
- Topical Antifungal
- Prescription Medicine
- Antifungal Treatment
Description
- Treatment of onychomycosis of the toenail or fingernail
- Treatment of Tinea Capitis
- Fungal infection of the skin caused by various organisms
- Indicated in the treatment of tinea infections of the skin and pityriasis versicolor
Dimensions
- Tablet: 250 mg
- Granules: 125mg/day, 187.5mg/day, 250mg/day
- Cream duration: 1-2 weeks
- Spray duration: 1-2 times daily for 1 week
Color options
- White (tablet)
- Granules (various)
- Cream (colorless)
- Spray (colorless)
Functions
- Inhibits biosynthesis of Ergosterol
- Fungicidal against certain microorganisms
- Inhibitor of the CYP450 2D6 isozyme
- External use only (cream)
Materials
- Terbinafine
- Hydrochloride
- Allylamine antifungal
Technical specifications
- Presence in breast milk of nursing mothers (tablet)
- Excretion in breast milk (cream)
Design elements
- Foetal toxicity and fertility studies in animals suggest no adverse effects (cream)
- Store below 30°C, protect from light
Usability features
- Apply to affected areas once or twice daily (cream)
- Cleanse and dry affected areas before application (cream)
- Applied once or twice daily, cleansed and dried thoroughly before application (spray)
Interaction
- Inhibitor of the CYP450 2D6 isozyme
- Co-administration may require dose reduction of 2D6-metabolized drugs
Contraindications
- Contra-indicated in individuals hypersensitive to terbinafine
Side effects
- Gastrointestinal symptoms
- Liver test abnormalities
- Rashes
- Urticaria
- Taste disturbances
- Symptomatic hepatic injury
- Serious skin reactions
- Severe neutropenia
- Thrombocytopenia
- Angioedema
- Allergic reactions
- Malaise
- Fatigue
- Vomiting
- Arthralgia
- Myalgia
- Hair loss
Pregnancy lactation
- Not recommended during pregnancy (tablet)
- Excreted in breast milk (cream)
- Not recommended in nursing mothers (cream)
Precautions warnings
- Discontinue if hepatic events occur (tablet)
- External use only, avoid contact with eyes (cream)
- Not recommended for patients with chronic or active liver disease
- Assess pre-existing liver disease before prescribing
Special populations
- Safety and efficacy not established in pediatric patients
- No evidence of different dosage or side-effects in elderly patients
Overdose effects
- Limited clinical experience
- Symptoms include nausea, vomiting, abdominal pain, dizziness, rash, frequent urination, headache
Therapeutic class
- Antifungal preparations
Storage conditions
- Store in a cool and dry place, below 30°C, protect from light