Mycofree 1% (Cream)
15 gm tube: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Drug international ltd |
| Also available as |
Title
- Mycofree Tablet
- Mycofree Granules
- Mycofree Cream
- Mycofree 1% Spray
Categories
- Antifungal Medicine
- Oral Antifungal
- Topical Antifungal
- Antifungal Treatment
Description
- Indicated for the treatment of onychomycosis of the toenail or fingernail due to dermatophytes
- Effective against Tinea Capitis, Tinea Pedis, Tinea Corporis, cutaneous candidiasis, and Pityriasis Versicolor
- Inhibits biosynthesis of Ergosterol via inhibition of Squalene Epoxidase enzyme
- Tablet dosage for fingernail onychomycosis: 250 mg once daily for 6 weeks
- Cream application for Tinea Corporis, Cruris: 1 to 2 weeks
- Granules dosage based on body weight for up to 6 weeks
- Interacts with CYP450 2D6-metabolized drugs
- Contraindicated in individuals hypersensitive to terbinafine
- Common side effects include gastrointestinal symptoms, liver test abnormalities, rashes, and taste disturbances
- Not recommended during pregnancy and lactation
- Rare cases of liver failure reported
- No established safety and efficacy in pediatric patients
- Storage conditions: below 30°C, protect from light
Dimensions
- Tablets: Various Sizes
- Cream Tube: Various Sizes
- Spray Bottle: Various Sizes
Color Options
- Tablet: White
- Granules: Powder Form
- Cream: White
- Spray: Transparent
Functions
- Antifungal Treatment
- Inhibits Ergosterol Biosynthesis
- Fungicidal Action
Materials
- Terbinafine
- Terbinafine Hydrochloride
Dosage & Administration
- Tablet dosage for toenail onychomycosis: 250 mg once daily for 12 weeks
- Cream application for Tinea Pedis: 1 week
- Cream application for Pityriasis Versicolor: 2 weeks
- Spray application for Tinea Pedis: once a day for 1 week
Interaction
- Inhibitor of CYP450 2D6 isozyme
- May require dose reduction of 2D6-metabolized drugs
Contraindications
- Hypersensitivity to Terbinafine
Side Effects
- Gastrointestinal Symptoms
- Liver Test Abnormalities
- Rashes
- Taste Disturbances
- Serious Skin Reactions
Pregnancy & Lactation
- Not recommended during pregnancy and lactation
- Excreted in breast milk
Precautions & Warnings
- Discontinue in case of liver injury
- Avoid contact with eyes for cream application
- Not recommended for patients with chronic or active liver disease
Use in Special Populations
- Safety and efficacy not established in pediatric patients
- No evidence of different dosages for elderly patients
Overdose Effects
- Limited clinical experience
- Taken up to 20 times the therapeutic daily dose without serious adverse reactions
Therapeutic Class
- Antifungal Preparations
Storage Conditions
- Cool and dry place
- Protect from light