Terbex 1% (Cream)
5 gm tube: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Terbinafine hydrochloride |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of onychomycosis of the toenail or fingernail
- Tinea Capitis
- Fungal infection of the skin
- Pityriasis (tinea) versicolor
Pharmacology
- Inhibition of biosynthesis of Ergosterol
- Fungicidal effect
- Active against Tricophyton Mentagrophyte and Trichophyton Rubrum
Dosage & Administration
- Daily dosage for toenail onychomycosis
- Duration of treatment for different types of fungal infections
- Application frequency for spray
Interaction
- Inhibition of CYP450 2D6 isozyme
- Drugs metabolized by CYP450 2D6 isozyme
- Careful monitoring for co-administration
Contraindications
- Hypersensitivity to terbinafine
Side Effects
- Gastrointestinal symptoms
- Liver test abnormalities
- Rashes
- Urticaria
- Taste disturbances
- Idiosyncratic and symptomatic hepatic injury
- Skin reactions
- Neutropenia
- Thrombocytopenia
- Allergic reactions
Pregnancy & Lactation
- Avoidance during pregnancy
- Presence in breast milk
- Excretion in breast milk
Precautions & Warnings
- Rare cases of liver failure
- Hepatic events in patients with liver disease
- Serious skin reactions
- External use for cream
- Assessment of pre-existing liver disease
- Hepatotoxicity risk assessment
Use in Special Populations
- Not established safety and efficacy in pediatric patients
- Elderly patient usage
Overdose Effects
- Limited clinical experience
- Symptoms of overdose
- No serious adverse reactions reported
Therapeutic Class
- Antifungal preparations
Storage Conditions
- Cool and dry storage
- Protection from light