Amezol 400 mg (Tablet)

Unit Price: ৳ 1.25 (100's pack: ৳ 125.00)

Medicine Details

Category Details
Generic Metronidazole
Company Cosmic pharma ltd
Also available as

Title

  • Amezol 400 mg Tablet

Categories

  • Antibiotic
  • Antiprotozoal
  • Amoebicide

Description

  • Amezol is a medication used for the treatment and prevention of viral, parasitic, and bacterial infections. It is available in tablet, suspension, vaginal gel, suppository, and IV infusion forms.

Dosage and administration

  • Recommended dosage for trichomoniasis in adults: 200 mg tid or 400 mg bid for 7 days
  • Recommended dosage for trichomoniasis in children: Varies based on age
  • Recommended dosage for intestinal amoebiasis in adults: 800 mg tid for 5 days
  • Recommended dosage for intestinal amoebiasis in children: Varies based on age
  • Recommended dosage for giardiasis in adults: 2 gm once daily for 3 days
  • Recommended dosage for giardiasis in children: Varies based on age
  • Recommended dosage for bacterial vaginosis in adults: 400 mg bid for 7 days
  • Recommended dosage for leg ulcers and pressure sores in adults: 400 mg tid for 7 days
  • Recommended dosage for anaerobic infections in adults: 800 mg initially and then 400 mg tid for 7 days
  • Recommended dosage for anaerobic infections in children: 7.5 mg/kg tid
  • Recommended dosage for surgical prophylaxis in adults: 400 mg tid started 24 hours before surgery for 1 day
  • Recommended dosage for vaginal gel: One applicator full intravaginally once or twice a day for 5 days
  • Recommended dosage for suppository for anaerobic infections: Varies for adults and children
  • Recommended dosage for suppository for surgical prophylaxis: Varies for adults and children
  • Recommended IV infusion dosage for adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute

Interactions

  • Potential interactions with disulfiram, alcohol, oral anticoagulants, lithium, cyclosporin, phenytoin, phenobarbital, 5-fluorouracil, and busulfan

Contraindications

  • Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy and lactation

  • US FDA Pregnancy Category B
  • Caution should be exercised when administered to a nursing woman

Precautions and warnings

  • Regular hematological tests, especially leucocyte count, recommended if administered longer than usual duration
  • Administer with caution to patients with hepatic encephalopathy

Special populations

  • Hepatic impairment: Amezol should be administered with caution, and daily dosage should be reduced for patients with hepatic encephalopathy
  • Renal impairment: No routine adjustment in the dosage of Amezol needed in patients with renal failure undergoing intermittent peritoneal dialysis or continuous ambulatory peritoneal dialysis

Overdose effects

  • Symptoms may include vomiting, ataxia, and slight disorientation. No specific antidote. Symptomatic and supportive treatment should be instituted

Therapeutic class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Storage conditions

  • Store below 30°C
  • Keep protected from light
  • Keep out of the reach of children

Faqs

  • What is amezol: Amezol 400 mg Tablet is an antibiotic medication that prevents the growth of bacteria and parasites.
  • Uses of amezol: Used for the treatment and prevention of viral, parasitic, and bacterial infections. Also controls various bacterial infections in different body parts.
  • Side effects of amezol: Some side effects include diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, and mouth ulcer.
  • Improvement timeline: It takes 1 or 2 days before improvement can be seen in health conditions after using Amezol 400 mg Tablet.
  • Contraindications: Amezol 400 mg Tablet should not be used in certain conditions such as hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
  • Pregnancy safety: Not recommended for use in pregnant women unless absolutely necessary.
  • Effectiveness of higher dose: Taking higher than the recommended dose of Amezol 400 mg Tablet can lead to increased chances of side effects.

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