Artemet 20 mg+120 mg (Tablet)
Unit Price: ৳ 20.00 (6 x 4: ৳ 480.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Artemether lumefantrine |
| Company | Incepta pharmaceuticals ltd |
Title
- Artemether and Lumefantrine Tablets
Categories
- Medicine
- Antimalarial
- Pharmaceutical
Description
- Artemether and Lumefantrine Tablets are indicated for the treatment of acute, uncomplicated malaria infections due to Plasmodium falciparum or mixed infections including P. falciparum. It is also recommended for malaria infections acquired in areas where the parasites may be resistant to other antimalarials. Additionally, it is suitable for the stand by emergency treatment of adults, children, and infants in isolated locations far from medical services.
Color Options
- White tablets
Functions
- Treatment of acute, uncomplicated malaria infections
- Stand by emergency treatment
Active Ingredients
- Artemether
- Lumefantrine
Substances
- Naturally occurring Artemisinin derivative
- Synthetic racemic fluorine mixture
Pharmacological Action
- Acts in the food vacuoles of malarial parasites
- Interferes with conversion of haem to haemozoin
- Generates reactive metabolites
- Inhibits nucleic acid-protein synthesis
Dosage Form
- Tablets
Dosage
- To be taken with high fat food or drinks such as milk
- Varied dosage for adults and children based on body weight
Pharmacokinetics
- Fixed ratio of 1:6 parts of Artemether and Lumefantrine
Adverse Effects
- Hypersensitivity
- Headache
- Dizziness
- Sleep disorder
- Vomiting
- Nausea
- Rash
- Fatigue
Contraindications
- Hypersensitivity to ingredients or excipients
- Severe malaria
- First trimester of pregnancy
- Family history of QTc interval prolongation or sudden death
- Disturbance of electrolyte balance
- Use of CYP2D6-metabolized drugs
Pregnancy and Lactation
- Contraindicated in pregnancy and lactation
- Not recommended for breastfeeding women due to long elimination half-life of Lumefantrine
Precautions
- Not evaluated for prophylaxis
- Not indicated for the treatment of cerebral malaria or other severe manifestations of severe malaria
Overdose Effects
- Symptomatic and supportive therapy in cases of suspected overdose
- ECG and blood potassium level monitoring
Therapeutic Class
- Anti-malarial drugs
Storage Conditions
- Keep below 30°C
- Away from light and moisture
- Keep out of the reach of children