Amobin 400 mg (Tablet)

Unit Price: ৳ 1.14 (100's pack: ৳ 114.00)

Medicine Details

Category Details
Generic Metronidazole
Company Doctors chemical works ltd
Also available as
Amobin 200 mg suspension Amobin 200 mg tablet

Product Title

Amobin 400 mg Tablet

Categories

  • Antibiotic
  • Antiprotozoal
  • Amoebicide
  • Antidiarrheal

Description

Amobin is indicated in the treatment of various diseases such as post-operative infections, septicaemia, bacterial vaginosis, amoebiasis, giardiasis, and dental infections caused by anaerobic organisms. It belongs to the therapeutic class of amoebicides, anti-diarrheal antiprotozoal.

Dimensions

N/A

Color Options

N/A

Functions

  • Prevention and treatment of post-operative infections
  • Treatment of various bacterial and parasitic infections
  • Controls liver, skin, joints, brain, and respiratory tract infections

Materials

  • Metronidazole
  • Nitroimidazole derivatives

Technical Specifications

  • Tablet and Suspension:
    • Trichomoniasis (Adults & Children):
      • 200-800 mg dosage regimen
      • 1-7 days treatment duration
    • Intestinal amoebiasis (Adults & Children):
      • 400-800 mg dosage regimen
      • 5-10 days treatment duration
    • Giardiasis (Adults & Children):
      • 500 mg-2 gm dosage
      • 3 days treatment duration
    • Acute ulcerative gingivitis (Adults & Children):
      • 200 mg-1 gm dosage
      • 3 days treatment duration
    • Bacterial Vaginosis (Adults & Children):
      • 400 mg-2 gm dosage
      • 7 days treatment duration
  • Vaginal Gel: 5 grams containing approximately 37.5 mg of Metronidazole, intravaginally once or twice a day for 5 days
  • Suppository (Anaerobic Infections & Surgical Prophylaxis):
    • Adults:
      • 1 g every 8-12 hours
    • Children (5-10 years):
      • 500 mg every 8-12 hours
  • IV Infusion:
    • Adults and children over 12 years: 500 mg 8 hourly at a rate of 5 ml/minute, maximum 4 g in 24 hours
    • Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute

Design Elements

  • Tablet
  • Suspension
  • Gel
  • Suppository
  • IV Infusion

Usability Features

  • Once daily dosing for some indications
  • Applicator for intravaginal administration
  • No dilution required for IV infusion

Interactions

  • Disulfiram
  • Alcohol
  • Warfarin type oral anticoagulant therapy
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or Nitroimidazole derivatives

Side Effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy & Lactation

  • FDA Pregnancy Category: B
  • Advisory: Use during pregnancy only if clearly needed, caution during lactation

Precautions & Warnings

  • Regular hematological tests for long-term use
  • Caution in hepatic encephalopathy patients

Use in Special Populations

  • Hepatic Impairment: Administered with caution, reduced dosage
  • Renal Impairment: No dosage reduction needed, efficient removal during haemodialysis

Overdose Effects

Vomiting, ataxia, slight disorientation observed, symptomatic and supportive treatment advised

Therapeutic Class

Amoebicides, Anti-diarrhoeal Antiprotozoal

Storage Conditions

Store below 30°C, protected from light, out of reach of children

Commonly Asked Questions

  • Answers:
    • Mechanism of action
    • Uses and side effects
    • Improvement duration
    • Contraindications
    • Safety during pregnancy
    • Optimal dosing
    • Quick tips for usage

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