Amotrex 200 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Aci limited |
| Also available as |
Title and Categories
- Amotrex 200 mg/5 ml Suspension
- Medicine
Dosage Forms
- Tablet
- Suspension
- Vaginal Gel
- Suppository
- IV Infusion
Dosage Administration
- Recommended dose of 200 mg tid or 400 mg bid for 7 days for Trichomoniasis in adults
- 800 mg in the morning and 1-2 gm at night for 2 days for Trichomoniasis
- 2 gm as a single dose for 1 day for Trichomoniasis
- 400-800 mg tid for 5-10 days for Extra-intestinal & Asymptomatic amoebiasis in adults
- 7.5 mg/kg tid for Anaerobic infections in children
Pharmacology
- Member of the imidazole class of antibacterial drugs
- Classified as an antiprotozoal agent
- Interacts with DNA and gives bactericidal action
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess
- Treatment of trichomoniasis, bacterial vaginosis, amoebiasis, giardiasis
- Treatment of acute ulcerative gingivitis, anaerobically infected leg ulcers
- Treatment of acute dental infections and antibiotic-associated pseudomembranous colitis
Interaction
- Potential interaction with Disulfiram, Alcohol, Lithium, Cyclosporin, Phenytoin, 5-Fluorouracil, Busulfan
- Recommended monitoring of anticoagulant therapy with warfarin during treatment
Contraindications
- Patients with a history of hypersensitivity to Metronidazole or Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
- FDA Pregnancy Category B
- Use during pregnancy only if clearly needed
- Excreted in human milk, caution during nursing
Precautions
- Regular hematological tests recommended during extended use
- Caution in patients with hepatic encephalopathy
- Warning for urine darkening
Overdose Effects
- Reported symptoms include vomiting, ataxia, slight disorientation
- No specific antidote, symptomatic and supportive treatment recommended
Drug Classes
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Store below 30°C
- Keep protected from light
- Keep out of the reach of children
Special Populations
- Caution advised in hepatic impairment, dosage adjustment necessary
- No dosage adjustment needed in renal impairment, caution in dialysis patients
Common Questions
- Uses of Amotrex 200 mg/5 ml Suspension
- Side effects and contraindications
- Safety during pregnancy
- Effectiveness in recommended dose
- Quick tips for usage