Dirozyl 400 mg (Tablet)
Unit Price: ৳ 1.70 (10 x 10: ৳ 170.00)
Strip Price: ৳ 17.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Acme laboratories ltd |
| Also available as |
Product Title
- Dirozyl 400 mg Tablet
Categories
- Antibiotic
- Antiprotozoal
- Amoebicide
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess
- Treatment of urogenital trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of all forms of amoebiasis
- Treatment of giardiasis
- Treatment of acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections due to anaerobic organisms
- Treatment of antibiotic-associated pseudomembranous colitis
Mode of Action
- Metronidazole is a member of the imidazole class of antibacterial drug
- Classified therapeutically as an antiprotozoal agent
- The 5-nitro group of Metronidazole is reduced by anaerobes metabolically
- Interacts with DNA and gives bactericidal action
Dosage & Administration
- Available in tablet, suspension, vaginal gel, suppository, and IV infusion forms
- Dosage varies based on age and specific conditions such as trichomoniasis, amoebiasis, giardiasis, gingivitis, bacterial vaginosis, leg ulcers, anaerobic infections, and surgical prophylaxis
Interactions
- Disulfiram
- Alcohol
- Lithium
- Cyclosporin
- Phenytoin or phenobarbital
- 5-Fluorouracil
- Busulfan
Contraindications
- Patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Excreted in human milk
- Caution recommended during pregnancy and lactation
Precautions & Warnings
- Regular hematological tests recommended if administered longer than usual duration
- Caution advised for patients with hepatic encephalopathy
Use in Special Populations
- Hepatic impairment
- Renal impairment
- No routine adjustment in the dosage for patients with renal failure undergoing intermittent peritoneal dialysis (IDP) or continuous ambulatory peritoneal dialysis (CAPD)
Overdose Effects
- Symptoms may include vomiting, ataxia, slight disorientation
- No specific antidote
- Symptomatic and supportive treatment recommended
Therapeutic Class
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Store below 30°C
- Keep protected from light
- Keep out of the reach of children
- Do not use after the expiry date
FAQs
- What is Dirozyl 400 mg Tablet?
- Uses of Dirozyl 400 mg Tablet
- Side effects of Dirozyl 400 mg Tablet
- Duration for improvements
- Contraindications
- Safety during pregnancy
- Recommended dose
Commonly Asked Questions
- Dirozyl 400 mg Tablet is an antibiotic medication that prevents the growth of bacterias and parasites
- Uses include treatment and prevention from viral, parasitic, and bacterial infections
- Side effects like diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, and mouth ulcer may be experienced
- 1 or 2 days may be needed to see improvement in health conditions
- Contraindications include hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
- Not recommended for use in pregnant women unless necessary
- Higher than recommended dose may increase side effects
Quick Tips
- Treats infections caused by bacteria and parasites
- May cause side effects like nausea, stomach upset, and a metallic taste in the mouth
- High dose or prolonged use increases the risk of side effects such as nerve damage
- Avoid alcohol during or after treatment
- Inform the doctor if you have liver disease