Filmet 200 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- The prevention of post-operative infections due to anaerobic bacteria
- The treatment of septicaemia and bacteraemia
- Treatment of urogenital trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of all forms of amoebiasis
- Treatment of giardiasis
- Treatment of acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections
- Treatment of antibiotic-associated pseudomembranous colitis
Pharmacology
Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically. Studies have demonstrated that the reduced form of this drug interacts with DNA and gives bactericidal action of Metronidazole.
Dosage & Administration
- Tablet and Suspension:
- Various dosages for different conditions and age groups
- Vaginal Gel: One applicator full of Metronidazole gel intravaginally once or twice a day for 5 days
- Suppository:
- Anaerobic Infections: Different dosages for adults and children
- Surgical Prophylaxis: Different dosages for adults and children
- IV Infusion:
- Adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute
- Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute
Interaction
- Disulfiram
- Alcohol
- Lithium
- Cyclosporin
- Phenytoin or phenobarbital
- 5-Fluorouracil
- Busulfan
Contraindications
Metronidazole is contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives.
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
US FDA Pregnancy Category of Metronidazole is B. Caution should be exercised when Metronidazole is administered to a nursing woman.
Precautions & Warnings
- Regular hematological tests recommended if administered longer than usual duration
- Caution with hepatic encephalopathy
Use in Special Populations
- Hepatic impairment
- Renal impairment
Overdose Effects
Single oral doses of Filmet, up to 12 g have been reported in suicide attempts and accidental overdoses. Symptoms were limited to vomiting, ataxia and slight disorientation.
Therapeutic Class
Amoebicides, Anti-diarrhoeal Antiprotozoal
Storage Conditions
Store below 30°C. Keep protected from light.
Common Questions about Filmet 200 mg Tablet
- What is Filmet 200 mg Tablet?: An antibiotic medication
- What are the uses of Filmet 200 mg Tablet?: Treatment and prevention from viral and parasitic infections
- What are the side effects of Filmet 200 mg Tablet?: Diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, mouth ulcer
- How long do I need to use Filmet 200 mg Tablet before I see improvement of my conditions?: 1 or 2 days
- What are the contraindications to Filmet 200 mg Tablet?: Hives, flushing, nasal congestion, dryness of the mouth, fever
- Is Filmet 200 mg Tablet safe to use when pregnant?: Not recommended unless absolutely necessary
- Will Filmet 200 mg Tablet be more effective if taken in more than the recommended dose?: No, increased chances of side effects