Flamyd 500 mg/100 ml (IV Infusion)
100 ml bottle: ৳ 53.40
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Title
- Flamyd 500 mg/100 ml Injection
Categories
- Medicine
- Medical Supplies
Description
- Flamyd is an antibiotic medication used for the treatment and prevention of various bacterial, parasitic, and viral infections. It is available in various forms such as tablets, suspension, vaginal gel, suppository, and IV infusion. The dosage and administration instructions vary based on the specific condition being treated, with recommended doses for adults and children as per the indication. It belongs to the therapeutic class of Amoebicides and Anti-diarrhoeal Antiprotozoal. The medicine is contraindicated in patients with a history of hypersensitivity to metronidazole or other nitroimidazole derivatives. Potential side effects may include metallic taste, nausea, vomiting, diarrhea, drowsiness, and rashes. It is categorized as US FDA Pregnancy Category B and caution is advised when administered to nursing women. The drug should be stored below 30°C, protected from light, and out of the reach of children. Precautions and warnings are mentioned for patients with hepatic encephalopathy, caution for compelling reasons if administered for longer durations, and an advisory about darkening of urine. Additionally, use in special populations such as those with hepatic or renal impairments are highlighted, along with overdose effects that may include vomiting, ataxia, and slight disorientation in case of massive overdoses.
Dimensions
- 500 mg/100 ml
Color Options
- NA
Functions
- Treats and prevents bacterial, parasitic, and viral infections
Materials
- Metronidazole
Technical Specifications
- Therapeutic class: Amoebicides, Anti-diarrhoeal Antiprotozoal
- US FDA Pregnancy Category: B
Design Elements
- NA
Usability Features
- Dosage varies based on the indication and patient age
Dosage and Administration
- Dosage and administration instructions are specific to the condition being treated, with recommended doses for adults and children as per the indication. Forms include tablets, suspension, vaginal gel, suppository, and IV infusion.
Mode of Action
- Metronidazole is an imidazole class antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically, interacting with DNA to provide bactericidal action.
Indications
- - Prevention of post-operative infections due to anaerobic bacteria
- - Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections caused by anaerobes, urogenital trichomoniasis, bacterial vaginosis, all forms of amoebiasis, giardiasis, acute ulcerative gingivitis, anaerobically infected leg ulcers and pressure sores, acute dental infections due to anaerobic organisms, antibiotic-associated pseudomembranous colitis
Interaction
- - Disulfiram: Psychotic reactions reported when used concurrently with Flamyd
- - Alcohol: Alcoholic beverages and drugs containing alcohol should be avoided during therapy
- - Lithium: Plasma levels of lithium may be increased by Flamyd
- - Cyclosporin: Serum cyclosporin and serum creatinine should be monitored when co-administration is necessary
- - Phenytoin or phenobarbital: Increased elimination of Flamyd resulting in reduced plasma levels
- - 5-Fluorouracil: Reduced clearance resulting in increased toxicity
- - Busulfan: Plasma levels of busulfan may be increased by Flamyd, leading to severe toxicity
Contraindications
- - Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- - Metallic taste
- - Nausea
- - Vomiting
- - Diarrhoea
- - Drowsiness
- - Rashes
Pregnancy & Lactation
- - US FDA Pregnancy category B
- - Caution advised during pregnancy and when administered to nursing women
Precautions & Warnings
- - Regular hematological tests recommended if Flamyd must be administered longer than usually recommended
- - Caution advised for hepatic encephalopathy patients
- - Patients should be warned that Flamyd may darken urine
Use in Special Populations
- - Hepatic impairment: Caution advised due to substantial impairment of Flamyd clearance
- - Renal impairment: Dosage adjustment may not be required in renal failure patients
- - Significant cumulation may occur in patients with hepatic encephalopathy and the resulting high plasma concentrations of Flamyd may contribute to the symptoms of encephalopathy
Overdose Effects
- - Single oral doses up to 12 g have been reported, leading to symptoms of vomiting, ataxia, and slight disorientation
- - No specific antidote for Flamyd overdosages
Storage Conditions
- - Store below 30°C
- - Keep protected from light
- - Keep medicines out of the reach of children
- - Do not use later than the date of expiry
Commonly Asked Questions
- - Flamyd 500 mg/100 ml IV Infusion treats and prevents various viral, parasitic, and bacterial infections
- - Some side effects may include diarrhea, headache, weakness, painful urination, and numbness
- - Improvement in health conditions may be seen within 1-2 days
- - Contraindications include specific conditions like hives, flushing, nasal congestion, and dryness of the mouth
- - Not recommended for pregnant women unless absolutely necessary
- - Higher than recommended doses may increase the chances of side effects such as diarrhea, excessive production of urine, headache, nausea, and more
Additional Information
- - No routine adjustment in the dosage of Flamyd need be made in patients with renal failure undergoing intermittent peritoneal dialysis (IDP) or continuous ambulatory peritoneal dialysis (CAPD)