Kemet 400 mg (Tablet)

Unit Price: ৳ 1.27 (100's pack: ৳ 127.00)

Medicine Details

Category Details
Generic Metronidazole
Company Kemiko pharmaceuticals ltd
Also available as

Title and Description

  • Kemet 400 mg Tablet
  • Kemet 400 mg Tablet is an antibiotic medication that prevents the growth of bacteria and parasites. It is used for the treatment and prevention of viral and parasitic infections, as well as bacterial infections such as cold, cough, flu, and vaginal infections. It also controls liver, skin, joints, brain, and respiratory tract infections.

Category

  • Medicine
  • Antibiotic
  • Antiprotozoal
  • Amoebicides
  • Anti-diarrhoeal

Dosage Forms

  • Tablet
  • Suspension
  • Vaginal Gel
  • Suppository
  • IV Infusion

Pharmacological Class

  • Imidazole Class
  • Antibacterial Drug
  • Antiprotozoal Agent
  • Nitroimidazole Derivatives

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections caused by anaerobes
  • Treatment of urogenital trichomoniasis
  • Bacterial vaginosis
  • All forms of amoebiasis
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers and pressure sores
  • Acute dental infections due to anaerobic organisms
  • Antibiotic associated pseudomembranous colitis

Mode of Action

  • Metronidazole is reduced by anaerobes metabolically
  • The reduced form of this drug interacts with DNA and provides bactericidal action

Interaction

  • Disulfiram: Psychotic reactions reported with concurrent use
  • Alcohol: Possibility of disulfiram-like reaction, potentiation of anticoagulant effect
  • Lithium: Plasma levels may be increased
  • Cyclosporin: Serum levels should be closely monitored
  • Phenytoin or phenobarbital: Increased elimination of Metronidazole
  • 5-Fluorouracil: Reduced clearance causing increased toxicity
  • Busulfan: Increased plasma levels may lead to severe toxicity

Contraindications

  • Patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side Effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy & Lactation

  • US FDA Pregnancy Category: B
  • Caution advised during pregnancy
  • Excreted in human milk

Precautions & Warnings

  • Compelling reasons may require regular hematological tests
  • Caution in patients with hepatic encephalopathy
  • May darken urine

Use in Special Populations

  • Hepatic Impairment: Kemet is mainly metabolized by hepatic oxidation
  • Renal Impairment: The elimination half-life remains unchanged

Overdose Effects

  • Symptoms limited to vomiting, ataxia, and slight disorientation
  • No specific antidote reported
  • Symptomatic and supportive treatment recommended

Therapeutic Class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Store below 30°C
  • Keep protected from light
  • Keep out of the reach of children
  • Do not use after the expiry date

Commonly Asked Questions

  • What is Kemet 400 mg Tablet?
  • What are the uses of Kemet 400 mg Tablet?
  • What are the side effects of Kemet 400 mg Tablet?
  • How long do I need to use Kemet 400 mg Tablet before I see improvement of my conditions?
  • What are the contraindications to Kemet 400 mg Tablet?
  • Is Kemet 400 mg Tablet safe to use when pregnant?
  • Will Kemet 400 mg Tablet be more effective if taken in more than the recommended dose?

Quick Tips

  • Kemet 400 mg Tablet treats infections caused by bacteria and parasites
  • May cause side effects like nausea, stomach upset, and a metallic taste in the mouth
  • High dose or prolonged use increases the risk of side effects such as nerve damage
  • Avoid alcohol consumption during or after treatment
  • Inform your doctor if you have liver disease

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