Melagyl 400 mg (Tablet)
Unit Price: ৳ 1.02 (100's pack: ৳ 102.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Reliance pharmaceuticals ltd |
| Also available as |
Title
- Melagyl 400 mg Tablet
Categories
- Antibiotics
- Antiparasitic
Description
- Melagyl 400 mg Tablet is an antibiotic medication that prevents the growth of bacteria and parasites. It is used for the treatment and prevention of viral and parasitic infections, as well as bacterial infections such as cold, cough, flu, and vaginal infections.
Pharmacology
- Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically. The reduced form of this drug interacts with DNA and provides bactericidal action.
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections caused by anaerobes
- Treatment of urogenital trichomoniasis
- Bacterial vaginosis
- Amoebiasis (intestinal, extra-intestinal disease and symptomless cyst passers)
- Giardiasis
- Acute ulcerative gingivitis
- Anaerobically infected leg ulcers and pressure sores
- Acute dental infections due to anaerobic organisms
- Antibiotic associated pseudomembranous colitis
DosageAndAdministration
- Dosage and administration vary depending on the condition being treated and the age of the patient. Specific dosages are provided for trichomoniasis, intestinal amoebiasis, extra-intestinal & asymptomatic amoebiasis, giardiasis, acute ulcerative gingivitis, acute dental infections, bacterial vaginosis, leg ulcers and pressure sores, anaerobic infections, surgical prophylaxis, vaginal gel, suppository, and IV infusion.
Interaction
- Disulfiram: Psychotic reactions reported with concurrent use
- Alcohol: Avoid consumption during therapy and for at least one day afterwards
- Oral anticoagulant therapy (warfarin type): Potentiation of the anticoagulant effect
- Lithium: Increased plasma levels
- Cyclosporin: Requires close monitoring of serum levels
- Phenytoin or phenobarbital: Increased elimination of Melagyl
- 5-Fluorouracil: Reduced clearance leading to increased toxicity
- Busulfan: Increased plasma levels leading to severe toxicity
Contraindications
- Patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
SideEffects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
PregnancyAndLactation
- PregnancyCategory: B
- UsageInPregnancy: Should be used during pregnancy only if clearly needed
- UsageInLactation: Caution should be exercised when administered to a nursing woman
PrecautionsAndWarnings
- Regular monitoring of hematological tests
- Caution in patients with hepatic encephalopathy
- May darken urine
UseInSpecialPopulations
- Hepatic impairment: Caution required due to substantial impairment of clearance
- Renal impairment: No reduction in dosage needed; metabolites retained
OverdoseEffects
- Reported symptoms include vomiting, ataxia, slight disorientation. No specific antidote; symptomatic and supportive treatment recommended
TherapeuticClass
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
StorageConditions
- Store below 30°C
- Protect from light
- Keep out of the reach of children
- Do not use later than the date of expiry
CommonlyAskedQuestions
- What is Melagyl 400 mg Tablet?
- What are the uses of Melagyl 400 mg Tablet?
- What are the side effects of Melagyl 400 mg Tablet?
- How long do I need to use Melagyl 400 mg Tablet before I see improvement of my conditions?
- What are the contraindications to Melagyl 400 mg Tablet?
- Is Melagyl 400 mg Tablet safe to use when pregnant?
- Will Melagyl 400 mg Tablet be more effective if taken in more than the recommended dose?
- Quick Tips for usage
StorageInformation
- Temperature: Below 30°C
- Protection: From light
- Safety: Keep out of the reach of children