Melagyl 200 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 25.75

Medicine Details

Category Details
Generic Metronidazole
Company Reliance pharmaceuticals ltd
Also available as
Melagyl 400 mg tablet

Title

Melagyl 200 mg/5 ml Suspension

Categories

  • Antibiotic
  • Antiprotozoal
  • Amoebicide

Indications

  • Prevention of post-operative infections
  • Treatment of septicaemia
  • Treatment of trichomoniasis
  • Treatment of bacterial vaginosis
  • Treatment of amoebiasis
  • Treatment of giardiasis
  • Treatment of acute ulcerative gingivitis
  • Treatment of anaerobic infections
  • Surgical prophylaxis

Pharmacology

Metronidazole is an antibacterial drug classified as an antiprotozoal agent, the reduced form interacts with DNA giving bactericidal action.

DosageAndAdministration

  • TabletAndSuspension:
    • TrichomoniasisAdultsChildrenOver10Yrs:
      • 200 mg tid or 400 mg bid for 7 days
      • 800 mg in the morning and 1-2 gm at night for 2 days
    • TrichomoniasisChildren:
      • Children 7-10 yrs: 100 mg tid
      • Children 3-7 yrs: 100 mg bid
      • Children 1-3 yrs: 50 mg tid
    • IntestinalAmoebiasisAdultsChildrenOver10Yrs: 800 mg tid for 5 days
    • IntestinalAmoebiasisChildren:
      • Children 7-10 yrs: 400 mg tid
      • Children 3-7 yrs: 200 mg qid
      • Children 1-3 yrs: 200 mg tid
    • ExtraIntestinalAndAsymptomaticAmoebiasis: 400-800 mg tid for 5-10 days
    • GiardiasisAdultsChildrenOver10Yrs: 2 gm once daily for 3 days
    • GiardiasisChildren:
      • Children 7-10 yrs: 1 gm once daily
      • Children 3-7 yrs: 600-800 mg once daily
      • Children 1-3 yrs: 500 mg once daily
    • AcuteUlcerativeGingivitis:
      • 200 mg tid for 3 days
      • Children 7-10 yrs: 100 mg tid
      • Children 3-7 yrs: 100 mg bid
      • Children 1-3 yrs: 50 mg tid
    • AcuteDentalInfectionsAdultsChildrenOver10Yrs: 200 mg tid for 3-7 days
    • BacterialVaginosisAdultsChildrenOver10Yrs:
      • 400 mg bid for 7 days
      • 2 gm as a single dose for 1 days
    • LegUlcersAndPressureSores: 400 mg tid for 7 days
    • AnaerobicInfectionsAdultsChildrenOver10Yrs: 800 mg initially and then 400 mg tid for 7 days
    • AnaerobicInfectionsChildren: Children 1-10 yrs: 7.5 mg/kg tid
    • SurgicalProphylaxisAdultsChildrenOver10Yrs: 400 mg tid started 24 hours before surgery for 1 days
    • SurgicalProphylaxisChildren: Children 1-10 yrs: 7.5 mg/kg tid
  • VaginalGel: One applicator full of Metronidazole gel intravaginally once or twice a day for 5 days.
  • Suppository:
    • AnaerobicInfectionsAdults: 1 g every 8 hours for 3 days, then 1 g every 12 hours
    • AnaerobicInfectionsChildren: 5-10 years: 500 mg every 8 hours for 3 days, then every 12 hours; Over 10 years: adult dose
    • SurgicalProphylaxisAdults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures
    • SurgicalProphylaxisChildren: 5-10 years: 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures
  • IVInfusion:
    • AdultsChildrenOver12Yrs: 500 mg 8 hourly at a rate of 5 ml/minute, maximum of 4 g should not be exceeded; 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute
    • ChildrenUnder12Yrs: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute

Interaction

  • Disulfiram
  • Alcohol
  • Oral anticoagulant therapy
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

SideEffects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

PregnancyAndLactation

  • PregnancyCategory: B
  • Guidance: Used during pregnancy only if clearly needed. Caution when administered to a nursing woman.

PrecautionsAndWarnings

  • Regular hematological tests if administered longer than recommended
  • Caution in patients with hepatic encephalopathy
  • May darken urine

UseInSpecialPopulations

  • HepaticImpairment: Caution in patients with hepatic encephalopathy, reduced dosage needed
  • RenalImpairment: No reduction in dosage needed, metabolites retained

OverdoseEffects

Symptomatic and supportive treatment

TherapeuticClass

  • Amoebicides
  • Antidiarrhoeal
  • Antiprotozoal

StorageConditions

Store below 30°C, protected from light, out of reach of children

CommonQuestionsAboutMelagyl200mg5mlSuspension

  • Questions:
    • What is Melagyl 200 mg/5 ml Suspension?
    • What are the uses of Melagyl 200 mg/5 ml Suspension?
    • What are the side effects of Melagyl 200 mg/5 ml Suspension?
    • How long do I need to use Melagyl 200 mg/5 ml Suspension before I see improvement of my conditions?
    • What are the contraindications to Melagyl 200 mg/5 ml Suspension?
    • Is Melagyl 200 mg/5 ml Suspension safe to use when pregnant?
    • Will Melagyl 200 mg/5 ml Suspension be more effective if taken in more than the recommended dose?
    • Quick Tips
  • Answers:
    • Antibiotic medication that prevents the growth of bacterias and parasites
    • Treatment and prevention from viral and parasitic infections, control of bacterial infections such as cold, cough, flu, and vaginal infections, controls liver, skin, joints, brain, and respiratory tract infections
    • Diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, mouth ulcer
    • 1 or 2 days
    • Hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
    • Not recommended unless absolutely necessary
    • No, increased chances of side effects
      • Treats infections caused by bacteria and parasites
      • May cause side effects like nausea and metallic taste
      • Used in high dose or for prolonged time increases the risk of side effects
      • Do not drink alcohol during or after treatment
      • Inform your doctor if you have liver disease

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