Metra 200 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 35.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Ad din pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess
- Treatment of pelvic abscess, pelvic cellulitis, and post-operative wound infections
- Treatment of urogenital trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of all forms of amoebiasis
- Treatment of giardiasis
- Treatment of acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections due to anaerobic organisms
- Treatment of antibiotic-associated pseudomembranous colitis
Pharmacology
- Member of the imidazole class of antibacterial drug
- Antiprotozoal agent
- 5-nitro group is reduced by anaerobes metabolically
- Interacts with DNA and gives bactericidal action
Dosage & Administration
- Available in Tablet, Suspension, Vaginal Gel, Suppository, and IV Infusion
- Various dosages for different diseases and age groups
Interaction
- Disulfiram: may cause psychotic reactions when used concurrently
- Alcohol: should not be consumed during therapy
- Warfarin: may potentiate the anticoagulant effect
- Lithium: may increase plasma levels of lithium
- Cyclosporin: serum levels should be closely monitored when co-administered
- Phenytoin or phenobarbital: may increase elimination of Metra
- 5-Fluorouracil: may reduce clearance of 5-fluorouracil
- Busulfan: may increase plasma levels of busulfan
Contraindications
- Hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Excreted in human milk
- Caution advised when administered to a nursing woman
Precautions & Warnings
- Hematological tests should be carried out regularly if administered longer than recommended duration
- Caution advised for patients with hepatic encephalopathy
Use in Special Populations
- Hepatic impairment: dosing adjustment and caution advised
- Renal impairment: no reduction in dosage required
- Hemodialysis: re-administration required immediately after dialysis
- Peritoneal dialysis: no routine adjustment in dosage required
Overdose Effects
- Reported symptoms include vomiting, ataxia, and slight disorientation
- No specific antidote available
Therapeutic Class
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Storage Conditions
- Store below 30°C
- Keep protected from light
- Keep out of reach of children
- Do not use after expiry date
Common Questions
- Treatment and prevention from viral and parasitic infections
- Controls bacterial infections such as cold, cough, flu, and vaginal infections
- Management of liver, skin, joints, brain, and respiratory tract infections
- Potential side effects include diarrhoea, headache, weakness, painful urination, and trouble sleeping
- Caution advised when used in pregnant women
- High doses may lead to increased chances of side effects like nerve damage