Metrion 400 mg (Tablet)
Unit Price: ৳ 2.01 (10 x 10: ৳ 200.60)
Strip Price: ৳ 20.06
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | General pharmaceuticals ltd |
| Also available as |
Title
- Metrion 400 mg Tablet
Categories
- Antibiotic Medication
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
Description
- Prevents growth of bacterias and parasites
- Treats and prevents viral, parasitic, and bacterial infections
- Controls liver, skin, joints, brain, and respiratory tract infections
- May cause metallic taste, nausea, vomiting, diarrhea, drowsiness, and rashes
- US FDA Pregnancy Category: B
Dimensions
- 400 mg Tablet
Color options
Functions
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, and post-operative wound infections
- Treats urogenital trichomoniasis, bacterial vaginosis, all forms of amoebiasis, giardiasis, acute ulcerative gingivitis, anaerobically infected leg ulcers and pressure sores, acute dental infections, and antibiotic-associated pseudomembranous colitis
- Interacts with DNA and gives bactericidal action
- Prevents the growth of bacterias and parasites
Materials
- Metronidazole
- Imidazole class of antibacterial drug
Technical specifications
- 5-nitro group is reduced by anaerobes metabolically
- Intravenous infusion requires no dilution
- Should not be mixed with other drugs prior to administration
Design elements
Usability features
- Recommended dose is intravaginally once or twice a day for 5 days
- Increased toxicity of 5-fluorouracil
- Plasma levels of busulfan may be increased
- No routine adjustment in the dosage need be made in patients with renal failure undergoing intermittent peritoneal dialysis (IDP) or continuous ambulatory peritoneal dialysis (CAPD)
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections, urogenital trichomoniasis, bacterial vaginosis, all forms of amoebiasis, giardiasis, acute ulcerative gingivitis, anaerobically infected leg ulcers and pressure sores, acute dental infections, and antibiotic-associated pseudomembranous colitis
Interaction
- Disulfiram may cause psychotic reactions
- Alcohol consumption may lead to a disulfiram-like reaction
- Potentiation of oral anticoagulant therapy (warfarin type)
- Increased plasma levels of lithium, serum cyclosporin, phenytoin or phenobarbital
- Reduced clearance of 5-fluorouracil
- Increased plasma levels of busulfan
Dosage administration
- Multiple dosage options for different conditions and age groups
- Recommended dose is intravaginally once or twice a day for 5 days
- Intravenous infusion requires specific dosage for adults and children over 12 years, and under 12 years
- Suppository dosage for adults and children
Contraindications
- Hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy lactation
- US FDA Pregnancy Category: B
- Excreted in human milk
- Caution should be exercised when administered to a nursing woman
Precautions warnings
- Regular hematological tests recommended if administered longer than usual duration
- Administered with caution to patients with hepatic encephalopathy
- May darken urine
Use in special populations
- Hepatic impairment: dosage reduction and caution in hepatic encephalopathy
- Renal impairment: no routine reduction in dosage needed, efficiently removed during haemodialysis
Overdose effects
- Reported symptoms include vomiting, ataxia, and slight disorientation
- No specific antidote
Storage conditions
- Store below 30°C
- Keep protected from light
- Keep out of the reach of children
- Do not use after the expiry date
Commonly asked questions
- What is Metrion 400 mg Tablet?
- What are the uses of Metrion 400 mg Tablet?
- What are the side effects of Metrion 400 mg Tablet?
- How long before improvement of conditions?
- Contraindications
- Use in pregnancy
- Effectiveness of higher than recommended dose
- Quick Tips