Metromax 400 mg (Tablet)

Unit Price: ৳ 1.35 (100's pack: ৳ 135.40)

Medicine Details

Category Details
Generic Metronidazole
Company Novo healthcare and pharma ltd
Also available as
Metromax 500 mg injection

Title

  • Metromax 400 mg Tablet

Categories

  • Medicine
  • Pharmacology
  • Antibacterial drug
  • Antiprotozoal agent
  • Amoebicides
  • Anti-diarrhoeal

Description

  • Metromax 400 mg Tablet is an antibiotic medication that prevents the growth of bacteria and parasites. It is used for the treatment and prevention of viral, parasitic, and bacterial infections such as cold, cough, flu, vaginal infections, liver, skin, joints, brain, and respiratory tract infections. It also controls liver, skin, joints, brain, and respiratory tract infections. Some side effects of Metromax 400 mg Tablet are diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, and mouth ulcer. Metromax 400 mg Tablet takes 1 or 2 days before improvement in health conditions is seen.

Color Options

  • White

Dosage Forms

  • Tablet
  • Suspension
  • Vaginal Gel
  • Suppository
  • IV Infusion

Dosage Recommendations

  • 200 mg tid or 400 mg bid for 7 days for Trichomoniasis in Adults & Children over 10 yrs
  • 800 mg in the morning and 1-2 gm at night for 2 days for Trichomoniasis in Adults & Children over 10 yrs
  • 2 gm as a single dose for 1 day for Trichomoniasis in Adults & Children over 10 yrs
  • 800 mg tid for 5 days for Intestinal amoebiasis in Adults & Children over 10 yrs
  • 400-800 mg tid for 5-10 days for Extra-intestinal & Asymptomatic amoebiasis in Adults & Children over 10 yrs
  • 2 gm once daily for 3 days for Giardiasis in Adults & Children over 10 yrs
  • 200 mg tid for 3 days for Acute ulcerative gingivitis in Adults & Children over 10 yrs
  • 1 g every 8 hours for 3 days, then 1 g every 12 hours for Anaerobic Infections in Adults
  • 500 mg every 8 hours for 3 days, then every 12 hours for Anaerobic Infections in Children
  • 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures for Surgical Prophylaxis in Adults
  • 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures for Surgical Prophylaxis in Children
  • 37.5 mg of Metronidazole) intravaginally once or twice a day for 5 days for Vaginal Gel
  • 400 mg tid for 7 days for Bacterial Vaginosis in Adults & Children over 10 yrs

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis, post-operative wound infections caused by anaerobes
  • Treatment of urogenital trichomoniasis
  • Bacterial vaginosis
  • All forms of amoebiasis
  • Giardiasis
  • Acute ulcerative gingivitis
  • Anaerobically infected leg ulcers and pressure sores
  • Acute dental infections due to anaerobic organisms
  • Antibiotic-associated pseudomembranus colitis

Pharmacology

  • Metronidazole is a member of the imidazole class of antibacterial drug
  • Classified therapeutically as an antiprotozoal agent
  • The 5-nitro group of Metronidazole is reduced by anaerobes metabolically
  • The reduced form interacts with DNA and gives bactericidal action

Interactions

  • Disulfiram
  • Alcohol
  • Oral anticoagulant therapy (warfarin type)
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side Effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy & Lactation

  • Pregnancy Category B
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Compelling reasons for longer administration must be monitored regularly with hematological tests
  • Caution in patients with hepatic encephalopathy
  • Metromax may darken urine

Special Populations Use

  • Hepatic impairment: Metromax should be administered with caution and reduced dosage
  • Renal impairment: Dosage needs no reduction but metabolites retention is not known in its clinical significance

Overdose Effects

  • Single oral doses of Metromax up to 12 g reported with limited symptoms like vomiting, ataxia, and slight disorientation
  • No specific antidote for Metromax overdosages

Therapeutic Class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

  • Store below 30°C
  • Protected from light
  • Keep out of reach of children
  • Do not use after expiry date

Commonly Asked Questions

  • What is Metromax 400 mg Tablet?
  • What are the uses of Metromax 400 mg Tablet?
  • What are the side effects of Metromax 400 mg Tablet?
  • How long do I need to use Metromax 400 mg Tablet before improvement of my conditions?
  • What are the contraindications to Metromax 400 mg Tablet?
  • Is Metromax 400 mg Tablet safe to use when pregnant?
  • Will Metromax 400 mg Tablet be more effective if taken in more than the recommended dose?
  • Quick tips: Metromax 400 mg Tablet treats infections, may cause side effects like nausea, stomach upset, and metallic taste, used in a high dose or for a prolonged time increases the risk of side effects, do not drink alcohol during or after treatment, inform your doctor if you have liver disease

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