Metroson 400 mg (Tablet)

Unit Price: ৳ 1.05 (100's pack: ৳ 105.00)

Medicine Details

Category	Details
Generic	Metronidazole
Company	Hudson pharmaceuticals ltd
Also available as	Metroson 200 mg suspension

Title

Metroson 400 mg Tablet

Description

Metroson 400 mg Tablet is an antibiotic medication used for treating and preventing viral, parasitic, and bacterial infections. It is also indicated for surgical prophylaxis and has various dosage regimens for different conditions such as trichomoniasis, amoebiasis, giardiasis, bacterial vaginosis, gingivitis, anaerobic infections, and pressure sores.

Color Options

White

Functions

Prevents growth of bacteria and parasites
Treats and prevents viral, parasitic, and bacterial infections
Surgical prophylaxis

Materials

Metronidazole
Imidazole class of antibacterial drug

Technical Specifications

Dosage Form: Tablet, Suspension, Vaginal Gel, Suppository, IV Infusion
Dosage Instructions:
- Trichomoniasis:
  - 200 mg tid or 400 mg bid for 7 days
  - 2 gm as a single dose for 1 day
- Intestinal Amoebiasis:
  - 800 mg tid for 5 days
- Extra-intestinal & Asymptomatic Amoebiasis:
  - 400-800 mg tid for 5-10 days
- Giardiasis:
  - 2 gm once daily for 3 days
- Acute Ulcerative Gingivitis:
  - 200 mg tid for 3 days
- Acute Dental Infections:
  - 200 mg tid for 3-7 days
- Bacterial Vaginosis:
  - 400 mg bid for 7 days
- Leg Ulcers and Pressure Sores:
  - 400 mg tid for 7 days
- Anaerobic Infections:
  - 800 mg initially and then 400 mg tid for 7 days
- Surgical Prophylaxis:
  - 400 mg tid started 24 hours before surgery for 1 day
  - IV Infusion: 500 mg 8 hourly at a rate of 5 ml/minute

Design Elements

Antibiotic
Imidazole class
5-nitro group
DNA interaction
Bactericidal action

Usability Features

Treatment of post-operative infections
Treatment of septicaemia, bacteraemia, peritonitis
Treatment of urogenital trichomoniasis
Treatment of bacterial vaginosis

Dimensions

Tablet: 400 mg
Vaginal Gel: 5 grams containing approximately 37.5 mg of Metronidazole

Indications

Prevention of post-operative infections due to anaerobic bacteria
Treatment of septicaemia, bacteraemia, peritonitis, brain abscess
Treatment of urogenital trichomoniasis
Treatment of bacterial vaginosis
Treatment of all forms of amoebiasis
Treatment of giardiasis
Treatment of acute ulcerative gingivitis

Pharmacology

Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically, and the reduced form interacts with DNA, providing bactericidal action.

Interaction

Disulfiram
Alcohol
Oral anticoagulant therapy
Lithium
Cyclosporin
Phenytoin or phenobarbital
5-Fluorouracil
Busulfan

Contraindications

Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

Side Effects

Metallic taste
Nausea
Vomiting
Diarrhoea
Drowsiness
Rashes

Pregnancy & Lactation

FDA Pregnancy Category: B
Usage in Pregnancy: Should be used only if clearly needed
Excretion in Human Milk: Excreted in human milk, caution advised in nursing women

Precautions & Warnings

Hematological tests for longer duration of use
Caution in patients with hepatic encephalopathy

Use in Special Populations

Hepatic Impairment: Requires caution, reduced daily dosage and monitoring
Renal Impairment:
- Elimination Half-Life: Remains unchanged
- Dialysis Patients: Requires re-administration after haemodialysis

Overdose Effects

Typical symptoms limited to vomiting, ataxia, and slight disorientation with no specific antidote

Therapeutic Class

Amoebicides
Anti-diarrhoeal
Antiprotozoal

Storage Conditions

Store below 30°C, protected from light, out of reach of children, not beyond expiry date

Common Questions

What is Metroson 400 mg Tablet?: An antibiotic medication preventing the growth of bacteria and parasites
What are the uses of Metroson 400 mg Tablet?: Treatment and prevention from viral, parasitic, and bacterial infections, control of various infections
What are the side effects of Metroson 400 mg Tablet?: Diarrhoea, headache, weakness, painful urination, and others
How long do I need to use Metroson 400 mg Tablet before I see improvement of my conditions?: 1-2 days before improvement
What are the contraindications to Metroson 400 mg Tablet?: Hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
Is Metroson 400 mg Tablet safe to use when pregnant?: Not recommended unless absolutely necessary
Will Metroson 400 mg Tablet be more effective if taken in more than the recommended dose?: No, will lead to increased side effects