Metrozen 400 mg (Tablet)
Unit Price: ৳ 1.70 (10 x 10: ৳ 170.00)
Strip Price: ৳ 17.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Zenith pharmaceuticals ltd |
| Also available as |
Title
- Metrozen 400 mg Tablet
Category
- Antibiotic
- Antiprotozoal
- Amoebicide
Indications
- Treatment of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia
- Treatment of bacteraemia
- Treatment of peritonitis
- Treatment of brain abscess
- Treatment of pelvic abscess
- Treatment of pelvic cellulitis
- Treatment of post-operative wound infections caused by anaerobes
- Urogenital trichomoniasis
- Bacterial vaginosis
- Amoebiasis
- Giardiasis
- Acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections due to anaerobic organisms
- Treatment of antibiotic-associated pseudomembranous colitis
Pharmacology
- Metronidazole is a member of the imidazole class of antibacterial drug
- Classified therapeutically as an antiprotozoal agent
- 5-nitro group of Metronidazole is reduced by anaerobes metabolically
- Interacts with DNA and gives bactericidal action of Metronidazole
DosageAdministration
- Dosage and administration varies based on the condition being treated
- Various dosages for adults and children over 10 years for different conditions like Trichomoniasis, Intestinal amoebiasis, Extra-intestinal & Asymptomatic amoebiasis, Giardiasis, Acute ulcerative gingivitis, Acute dental infections, Bacterial Vaginosis, Leg ulcers and pressure sores, Anaerobic infections, Surgical prophylaxis
- Different dosages for children in various age groups for respective conditions
Interaction
- Interaction with Disulfiram
- Interaction with Alcohol
- Interaction with Oral anticoagulant therapy (warfarin type)
- Interaction with Lithium
- Interaction with Cyclosporin
- Interaction with Phenytoin or phenobarbital
- Interaction with 5-Fluorouracil
- Interaction with Busulfan
Contraindications
- Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
SideEffects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
PregnancyLactation
- US FDA Pregnancy Category of Metronidazole is B
- No adequate and well-controlled studies in pregnant women
- Excretion in human milk
- Caution recommended for nursing women
PrecautionsWarnings
- Hematological tests recommended if administered longer than recommended duration
- Caution in patients with hepatic encephalopathy
- Potential urine darkening
UseInSpecialPopulations
- Hepatic impairment
- Renal impairment
OverdoseEffects
- Reported single oral doses of up to 12 g
- Symptoms limited to vomiting, ataxia, slight disorientation
- No specific antidote
- Symptomatic and supportive treatment should be instituted in case of suspected massive overdosages
TherapeuticClass
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
StorageConditions
- Store below 30°C
- Keep protected from light
- Keep out of reach of children
- Do not use after expiry date
CommonQuestions
- What is Metrozen 400 mg Tablet?
- Uses of Metrozen 400 mg Tablet
- Side effects of Metrozen 400 mg Tablet
- Duration for improvement of conditions
- Contraindications to Metrozen 400 mg Tablet
- Safety during pregnancy
- Recommended dosing
CommonQuestionsQuickTips
- Metrozen 400 mg Tablet treats infections caused by bacteria and parasites
- May cause side effects like nausea, stomach upset, metallic taste
- High dose or prolonged use increases risk of side effects
- Avoid alcohol during or after treatment
- Inform doctor about liver disease for dosage adjustments