Metryl 500 mg (Tablet)
Unit Price: ৳ 2.00 (10 x 10: ৳ 200.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Opsonin pharma ltd |
| Also available as |
Title
- Metryl 500 mg Tablet
Categories
- Antibiotic
- Antiprotozoal
- Amoebicide
Description
- Indications:
- Prevention of post-operative infections
- Treatment of septicaemia
- Treatment of bacteraemia
- Treatment of trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of amoebiasis
- Treatment of giardiasis
- Treatment of gingivitis
- Treatment of anaerobic infections
- Pharmacology:
- Belongs to the imidazole class of antibacterial drug
- An antiprotozoal agent
- Interacts with DNA to produce bactericidal action
- Dosage and administration:
- Tablet and suspension:
- Trichomoniasis adults and children over 10 yrs:
- 200 mg tid for 7 days
- 400 mg bid for 7 days
- 800 mg in the morning and 1-2 gm at night for 2 days
- Trichomoniasis children:
- 100 mg tid (7-10 yrs)
- 100 mg bid (3-7 yrs)
- 50 mg tid (1-3 yrs)
- Intestinal amoebiasis adults and children over 10 yrs:
- 800 mg tid for 5 days
- Intestinal amoebiasis children:
- 400 mg tid (7-10 yrs)
- 200 mg qid (3-7 yrs)
- 200 mg tid (1-3 yrs)
- Extra-intestinal & asymptomatic amoebiasis adults and children over 10 yrs:
- 400-800 mg tid for 5-10 days
- Extra-intestinal & asymptomatic amoebiasis children:
- 200-400 mg tid (7-10 yrs)
- 100-200 mg qid (3-7 yrs)
- 100-200 mg tid (1-3 yrs)
- Giardiasis adults and children over 10 yrs:
- 2 gm once daily for 3 days
- Giardiasis children:
- 1 gm once daily (7-10 yrs)
- 600-800 mg once daily (3-7 yrs)
- 500 mg once daily (1-3 yrs)
- Acute ulcerative gingivitis adults and children over 10 yrs:
- 200 mg tid for 3 days
- Acute ulcerative gingivitis children:
- 100 mg tid (7-10 yrs)
- 100 mg bid (3-7 yrs)
- 50 mg tid (1-3 yrs)
- Acute dental infections adults and children over 10 yrs:
- 200 mg tid for 3-7 days
- Bacterial vaginosis adults and children over 10 yrs:
- 400 mg bid for 7 days
- 2 gm as a single dose for 1 day
- Leg ulcers and pressure sores adults and children over 10 yrs:
- 400 mg tid for 7 days
- Anaerobic infections adults and children over 10 yrs:
- 800 mg initially and then 400 mg tid for 7 days
- Anaerobic infections children:
- 7.5 mg/kg tid (1-10 yrs)
- Surgical prophylaxis adults and children over 10 yrs:
- 400 mg tid started 24 hours before surgery for 1 day
- Surgical prophylaxis children:
- 7.5 mg/kg tid (1-10 yrs)
- Trichomoniasis adults and children over 10 yrs:
- Vaginal gel: One applicator full of Metronidazole gel (5 grams containing approximately 37.5 mg of Metronidazole) intravaginally once or twice a day for 5 days
- Suppository:
- Anaerobic infections:
- Adults: 1 g every 8 hours for 3 days, then 1 g every 12 hours
- Children: 500 mg every 8 hours for 3 days (5-10 years), then every 12 hours; Over 10 years adult dose
- Surgical prophylaxis:
- Adults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures
- Children: 500 mg 2 hours before surgery; up to 3 further doses of 500 mg may be given every 8 hours for high risk procedures
- Anaerobic infections:
- Iv infusion:
- Adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute for 7 days (can be extended for reinfection cases); for surgical prophylaxis, administration shortly before surgery followed by 8-hourly doses for the next 24 hours
- Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute
- Tablet and suspension:
- Interaction:
- Disulfiram
- Alcohol
- Lithium
- Cyclosporin
- Phenytoin or phenobarbital
- 5-Fluorouracil
- Busulfan
- Contraindications:
- Hypersensitivity to Metronidazole or other Nitroimidazole derivatives
- Side effects:
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
- Pregnancy and lactation:
- Pregnancy category: B
- Caution in lactation: Caution should be exercised when Metronidazole is administered to a nursing woman
- Precautions and warnings:
- Compelling reasons for longer administration require regular hematological tests
- Caution in hepatic encephalopathy patients
- Metryl may darken urine
- Special populations:
- Hepatic impairment: Metryl should be administered with caution and reduced dosage in advanced hepatic insufficiency
- Renal impairment: No need for dosage reduction; Metryl and metabolites are efficiently removed during haemodialysis
- Overdose effects:
- Vomiting
- Ataxia
- Slight disorientation
- Therapeutic class:
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
- Storage conditions: Store below 30°C, protected from light, and out of the reach of children
- Common questions:
- What is Metryl 500 mg Tablet?
- What are the uses of Metryl 500 mg Tablet?
- What are the side effects of Metryl 500 mg Tablet?
- How long do I need to use Metryl 500 mg Tablet before I see improvement of my conditions?
- What are the contraindications to Metryl 500 mg Tablet?
- Is Metryl 500 mg Tablet safe to use when pregnant?
- Will Metryl 500 mg Tablet be more effective if taken in more than the recommended dose?