Phidazole 200 mg/5 ml (Oral Suspension)

60 ml bottle: ৳ 24.50

Medicine Details

Category Details
Generic Metronidazole
Company Pharmadesh laboratories ltd
Also available as
Phidazole 400 mg tablet

Title

Phidazole 200 mg/5 ml Suspension

Categories

  • Medicine
  • Antibiotic
  • Antiprotozoal
  • Amoebicide
  • Anti-diarrheal

Description

Phidazole is an antibiotic medication used for the treatment and prevention of various bacterial, viral, and parasitic infections, including trichomoniasis, amoebiasis, bacterial vaginosis, giardiasis, and ulcerative gingivitis.

DosageForm

Tablet, Suspension, Vaginal Gel, Suppository, IV Infusion

Pharmacology

  • Belongs to the imidazole class of antibacterial drug
  • Acts as an antiprotozoal agent
  • Interacts with DNA and exhibits bactericidal action

DosageAndAdministration

  • TabletAndSuspension:
    • AdultsAndChildrenOver10Years: 200 mg tid or 400 mg bid for 7 days
    • TrichomoniasisChildren: Children 1-3 yrs: 50 mg tid
    • IntestinalAmoebiasisAdultsAndChildrenOver10Years: 800 mg tid for 5 days
    • GiardiasisChildren: Children 1-3 yrs: 500 mg once daily
  • VaginalGel: One applicator full of Metronidazole gel intravaginally once or twice a day for 5 days
  • Suppository:
    • AnaerobicInfectionsChildren: 5-10 years: 500 mg every 8 hours for 3 days
    • SurgicalProphylaxisAdults: 1 g 2 hours before surgery; up to 3 further doses of 1 g may be given every 8 hours for high risk procedures
  • IvInfusion:
    • AdultsAndChildrenOver12Years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute
    • ChildrenUnder12Years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute

Interactions

  • Disulfiram
  • Alcohol
  • Lithium
  • Cyclosporin
  • Phenytoin or phenobarbital
  • 5-Fluorouracil
  • Busulfan

Contraindications

  • Hypersensitivity to Metronidazole or other Nitroimidazole derivatives

SideEffects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhea
  • Drowsiness
  • Rashes

PregnancyAndLactation

  • PregnancyCategory: B
  • Advisory: Use during pregnancy only if clearly needed. Caution should be exercised when administered to a nursing woman.

PrecautionsAndWarnings

  • HematologicalTests: Especially leucocyte count should be carried out regularly if administered longer than recommended duration
  • HepaticEncephalopathy: Administer with caution
  • UrineDiscoloration: Patients should be warned that Phidazole may darken urine

SpecialPopulations

  • HepaticImpairment: Administer with caution; dosage should be reduced in the presence of advanced hepatic insufficiency
  • RenalImpairment: No routine adjustment in dosage is needed in patients with renal failure undergoing intermittent peritoneal dialysis or continuous ambulatory peritoneal dialysis

OverdoseEffects

Symptomatic and supportive treatment should be instituted in case of suspected massive overdosages

TherapeuticClass

Amoebicides, Anti-diarrheal, Antiprotozoal

StorageConditions

Store below 30°C, protected from light, and out of the reach of children. Do not use after expiry date.

CommonlyAskedQuestions

  • SuspensionDescription: An antibiotic medication that prevents the growth of bacterias and parasites
  • Uses: Treats and prevents viral, parasitic, and bacterial infections, including cold, cough, flu, vaginal infections, liver, skin, joints, brain, and respiratory tract infections
  • SideEffects:
    • Diarrhea
    • Headache
    • Weakness
    • Painful urination
    • Trouble sleeping
    • Numbness
    • Muscle weakness
    • Mouth ulcer
  • TimeToImprovement: 1 or 2 days
  • Contraindications: Hives, flushing, nasal congestion, dryness of the mouth, fever
  • PregnancySafety: Not recommended unless absolutely necessary
  • Dosing:
    • Treats: Infections caused by bacteria and parasites
    • Caution: High dose or prolonged use increases the risk of side effects such as nerve damage

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