Varizil 400 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Drug international ltd |
| Also available as |
Title
Varizil 400 mg Tablet
Categories
- Antibiotic
- Antiprotozoal
- Amoebicide
Description
Varizil is indicated in the treatment of various diseases including post-operative infections, septicaemia, urogenital trichomoniasis, bacterial vaginosis, amoebiasis, giardiasis, gingivitis, anaerobic infections, and more.
DosageFormAndStrength
Tablet and Suspension, Vaginal Gel, Suppository, IV Infusion
Indications
- Prevention of post-operative infections
- Treatment of septicaemia
- Treatment of trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of amoebiasis
- Treatment of giardiasis
- Treatment of gingivitis
- Treatment of anaerobic infections
Pharmacology
Metronidazole is a member of the imidazole class of antibacterial drugs and is classified as an antiprotozoal agent. The reduced form of Metronidazole interacts with DNA, providing bactericidal action.
DosageAndAdministration
- Various dosages for trichomoniasis based on age
- Dosages for intestinal amoebiasis based on age
- Dosages for extra-intestinal and asymptomatic amoebiasis based on age
- Dosages for giardiasis based on age
- Dosages for acute ulcerative gingivitis based on age
- Dosages for acute dental infections
- Dosages for bacterial vaginosis
- Dosages for leg ulcers and pressure sores
- Dosages for anaerobic infections
- Dosages for surgical prophylaxis based on age
- Dosage for vaginal gel
- Dosage for suppository
- Dosage for IV infusion in adults and children over 12 years
- Dosage for IV infusion in children under 12 years
Interaction
- Disulfiram interaction
- Alcohol interaction
- Lithium interaction
- Cyclosporin interaction
- Phenytoin or phenobarbital interaction
- 5-Fluorouracil interaction
- Busulfan interaction
Contraindications
Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
SideEffects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
PregnancyAndLactation
US FDA Pregnancy Category B. Caution advised during pregnancy and lactation.
PrecautionsAndWarnings
- Regular hematological tests recommended for longer use
- Caution in patients with hepatic encephalopathy
- Warning about urine discoloration
SpecialPopulations
- Caution in hepatic impairment
- No reduction in dosage in renal impairment
- Efficient removal of Varizil in patients undergoing haemodialysis
- No routine adjustment in patients with renal failure undergoing intermittent peritoneal dialysis or continuous ambulatory peritoneal dialysis
OverdoseEffects
Symptoms limited to vomiting, ataxia, and slight disorientation. No specific antidote. Symptomatic and supportive treatment advised.
TherapeuticClass
- Amoebicides
- Anti-diarrhoeal
- Antiprotozoal
StorageConditions
Store below 30°C. Protect from light. Keep out of reach of children. Do not use after expiry date.
CommonQuestions
- Question: What is Varizil 400 mg Tablet?
- Answer: An antibiotic medication that prevents the growth of bacteria and parasites.
- Question: What are the uses of Varizil 400 mg Tablet?
- Answer: Treatment and prevention from viral and parasitic infections. Control of bacterial infections such as cold, cough, flu, and vaginal infections.
- Question: What are the side effects of Varizil 400 mg Tablet?
- Answer: Diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, and mouth ulcer.
- Question: How long do I need to use Varizil 400 mg Tablet before I see improvement of my conditions?
- Answer: 1 or 2 days.
- Question: What are the contraindications to Varizil 400 mg Tablet?
- Answer: Conditions such as hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
- Question: Is Varizil 400 mg Tablet safe to use when pregnant?
- Answer: Not recommended unless absolutely necessary.
- Question: Will Varizil 400 mg Tablet be more effective if taken in more than the recommended dose?
- Answer: No, it can increase the risk of side effects.
- Question: Quick Tips
- Answer: Treats infections caused by bacteria and parasites. May cause side effects such as nausea, stomach upset, and metallic taste in the mouth. High dose or prolonged use increases the risk of side effects. Avoid alcohol during or after treatment. Inform doctor if you have liver disease.