Metron 400 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Leon pharmaceuticals ltd |
Title
Metron 400 mg Tablet
Categories
- Antibiotic
- Antiprotozoal
- Amoebicide
- Antidiarrheal
Description
Metron 400 mg Tablet is used for the treatment and prevention of viral, parasitic, and bacterial infections. It is also utilized to control infections in the liver, skin, joints, brain, and respiratory tract.
Dosage
- 200 mg tid or 400 mg bid for 7 days
- 800 mg in the morning and 1-2 gm at night for 2 days
- 2 gm as a single dose for 1 day
Age group dosage
- Adults: 200-800 mg tid for various conditions
- Children:
- 7-10 years: 100-400 mg tid
- 3-7 years: 100-200 mg qid
- 1-3 years: 50-200 mg tid
Administration methods
- Tablet
- Suspension
- Vaginal Gel
- Suppository
- IV Infusion
Side effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy category
B
Storage conditions
Store below 30°C, protected from light, and out of reach of children. Do not use after the expiry date.
Contraindications
Metron 400 mg Tablet is contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives.
Pharmacology
Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. It interacts with DNA to give bactericidal action.
Interaction
- Disulfiram
- Alcohol
- Oral anticoagulant therapy
- Lithium
- Cyclosporin
- Phenytoin or phenobarbital
- 5-Fluorouracil
- Busulfan
Precautions and warnings
- Regular hematological tests recommended for prolonged use
- Administer with caution to patients with hepatic encephalopathy
- May darken urine
Special populations
- Hepatic impairment: Dosage should be reduced and administered with caution
- Renal impairment: No reduction in dosage needed, but metabolites may accumulate
Overdose effects
Symptomatic and supportive treatment should be instituted in case of suspected massive overdosages.
Therapeutic class
- Amoebicides
- Antidiarrheal
- Antiprotozoal
Common questions
- What is it: An antibiotic medication that prevents the growth of bacteria and parasites.
- Uses: For the treatment and prevention of viral, parasitic, and bacterial infections, as well as control of various specific infections.
- Side effects: Include diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, and mouth ulcer.
- Improvement time: 1 or 2 days before improvement is seen
- Contraindications: Hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
- Safety during pregnancy: Not recommended unless absolutely necessary
- Effectiveness of higher dose: Not more effective and may lead to increased side effects