Protec 400 mg (Tablet)

Unit Price: ৳ 1.08 (100's pack: ৳ 108.00)

Medicine Details

Category Details
Generic Metronidazole
Company Hallmark pharmaceuticals ltd

Indications

  • Prevention of post-operative infections due to anaerobic bacteria
  • Treatment of septicaemia, bacteraemia, peritonitis, brain abscess
  • Treatment of urogenital trichomoniasis
  • Treatment of bacterial vaginosis
  • Treatment of all forms of amoebiasis
  • Treatment of giardiasis
  • Treatment of acute ulcerative gingivitis
  • Treatment of anaerobically infected leg ulcers and pressure sores
  • Treatment of acute dental infections due to anaerobic organisms
  • Treatment of antibiotic associated pseudomembranus colitis

Pharmacology

Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent.

Dosage & Administration

  • Different dosages for trichomoniasis in adults and children
  • Specific dosages for intestinal amoebiasis and extra-intestinal & asymptomatic amoebiasis
  • Dosages for giardiasis in adults and children
  • Dosages for acute ulcerative gingivitis in adults and children
  • Treatment dosages for bacterial vaginosis, leg ulcers and pressure sores, anaerobic infections, and surgical prophylaxis
  • Dosage recommendations for the vaginal gel, suppository, and IV infusion

Interaction

  • Disulfiram may cause psychotic reactions when used concurrently
  • Avoid alcohol consumption during therapy
  • Potentiation of anticoagulant effect with oral anticoagulant therapy
  • Possible interactions with lithium, cyclosporin, phenytoin, phenobarbital, 5-fluorouracil, and busulfan

Contraindications

Contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives.

Side Effects

  • Metallic taste
  • Nausea
  • Vomiting
  • Diarrhoea
  • Drowsiness
  • Rashes

Pregnancy & Lactation

US FDA Pregnancy Category of Metronidazole is B. No adequate and well-controlled studies in pregnant women. Caution should be exercised when administered to a nursing woman.

Precautions & Warnings

  • Regular hematological tests recommended for prolonged use
  • Use with caution in patients with hepatic encephalopathy
  • May darken urine

Use in Special Populations

  • Recommended caution in patients with hepatic impairment
  • Dosage adjustment may be necessary in renal impairment
  • No routine adjustment in the dosage for patients undergoing dialysis

Overdose Effects

Symptoms limited to vomiting, ataxia, and slight disorientation for reported overdoses up to 12 g. No specific antidote available.

Therapeutic Class

Amoebicides, Anti-diarrhoeal Antiprotozoal

Storage Conditions

Store below 30°C. Keep protected from light. Keep medicines out of the reach of children. Do not use later than the date of expiry.

Common Questions about Protec 400 mg Tablet

  • Protec 400 mg Tablet is an antibiotic medication that prevents the growth of bacterias and parasites
  • Used for the treatment and prevention from viral and parasitic infections
  • Common side effects include diarrhoea, headache, weakness, and painful urination
  • Improvement may be seen in 1 or 2 days of use

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