Vigil 200 mg/5 ml (Oral Suspension)
60 ml bottle: ৳ 22.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Metronidazole |
| Company | Salton pharmaceuticals ltd |
| Also available as |
Indications
- Prevention of post-operative infections due to anaerobic bacteria
- Treatment of septicaemia, bacteraemia, peritonitis, brain abscess, pelvic abscess, pelvic cellulitis
- Treatment of urogenital trichomoniasis
- Treatment of bacterial vaginosis
- Treatment of all forms of amoebiasis
- Treatment of giardiasis
- Treatment of acute ulcerative gingivitis
- Treatment of anaerobically infected leg ulcers and pressure sores
- Treatment of acute dental infections due to anaerobic organisms
- Treatment of antibiotic associated pseudomembranus colitis
Pharmacology
Metronidazole is a member of the imidazole class of antibacterial drug and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Metronidazole is reduced by anaerobes metabolically, and the reduced form of this drug interacts with DNA and gives bactericidal action of Metronidazole.
Dosage & Administration
- Tablet and Suspension:
- Various dosages for trichomoniasis in adults and children
- Dosages for intestinal amoebiasis in adults and children
- Dosages for extra-intestinal & asymptomatic amoebiasis in adults and children
- Dosages for giardiasis in adults and children
- Dosages for acute ulcerative gingivitis in adults and children
- Dosages for acute dental infections in adults and children
- Dosages for bacterial vaginosis in adults and children
- Dosages for leg ulcers and pressure sores in adults and children
- Dosages for anaerobic infections in adults and children
- Dosages for surgical prophylaxis in adults and children
- Vaginal Gel: Recommended dosage is one applicator full intravaginally once or twice a day for 5 days
- Suppository: Different dosages for anaerobic infections and surgical prophylaxis in adults and children
- IV Infusion:
- Adults and children over 12 years: Infuse 500 mg 8 hourly at a rate of 5 ml/minute, not to exceed 4 g in 24 hours
- Children under 12 years: 7.5 mg/kg body weight/day every 8 hours at a rate of 5 ml/minute
Interaction
- Disulfiram: May cause psychotic reactions when used concurrently with Vigil
- Alcohol: Should not be consumed during therapy and for at least one day afterwards
- Oral anticoagulant therapy: May potentiate the anticoagulant effect
- Lithium: May increase plasma levels of lithium
- Cyclosporin: Serum levels should be closely monitored when co-administered
- Phenytoin or phenobarbital: May increase elimination of Vigil
- 5-Fluorouracil: May reduce clearance of 5-fluorouracil
- Busulfan: May increase plasma levels of busulfan
Contraindications
Metronidazole is contraindicated in patients with a history of hypersensitivity to Metronidazole or other Nitroimidazole derivatives
Side Effects
- Metallic taste
- Nausea
- Vomiting
- Diarrhoea
- Drowsiness
- Rashes
Pregnancy & Lactation
- Pregnancy Category: B
- Recommendation: Should be used during pregnancy only if clearly needed, caution should be exercised when administered to a nursing woman
Precautions & Warnings
- Regular hematological tests recommended for longer duration usage
- Caution in patients with hepatic encephalopathy
- May darken urine
Use in Special Populations
- Hepatic impairment: Dosage should be reduced and administered with caution
- Renal impairment: Dosage needs no reduction, metabolites are retained in patients
Overdose Effects
Symptomatic and supportive treatment recommended, no specific antidote available
Therapeutic Class
Amoebicides, Anti-diarrhoeal Antiprotozoal
Storage Conditions
Store below 30°C, keep protected from light, keep out of the reach of children, do not use after the date of expiry
Commonly Asked Questions
- What is Vigil 200 mg/5 ml Suspension?: An antibiotic medication that prevents the growth of bacterias and parasites
- What are the uses of Vigil 200 mg/5 ml Suspension?: Treatment and prevention from viral and parasitic infections, and bacterial infections such as cold, cough, flu, and vaginal infections
- What are the side effects of Vigil 200 mg/5 ml Suspension?: Diarrhoea, headache, weakness, painful urination, trouble sleeping, numbness, muscle weakness, mouth ulcer
- How long do I need to use Vigil 200 mg/5 ml Suspension before I see improvement of my conditions?: 1 or 2 days before improvement is seen
- What are the contraindications to Vigil 200 mg/5 ml Suspension?: Should not be used in certain conditions such as hives, flushing, nasal congestion, dryness of the mouth, fever, etc.
- Is Vigil 200 mg/5 ml Suspension safe to use when pregnant?: Not recommended for use in pregnant women unless absolutely necessary
- Will Vigil 200 mg/5 ml Suspension be more effective if taken in more than the recommended dose?: No, may lead to increased chances of side effects