Secnid DS 1000 mg (Tablet)

Unit Price: ৳ 20.06 (5 x 2: ৳ 200.60)
Strip Price: ৳ 40.12

Medicine Details

Category Details
Generic Secnidazole
Company Square pharmaceuticals plc

Indications

  • Intestinal Amoebiasis
  • Hepatic Amoebiasis
  • Urethritis due to Trichomonas vaginalis
  • Vaginitis due to Trichomonas vaginalis
  • Giardiasis

Pharmacology

Rapid absorption following oral administration, maximum serum level obtained after 3 hours, plasma elimination half-life of about 20 hours, eliminated via urine

Dosage & Administration

  • Acute Intestinal Amoebiasis:
    • Adults: 2 gm single dose, taken preferably just before a meal
    • Children: 30 mg/kg single dose, taken preferably just before a meal
  • Asymptomatic Amoebiasis:
    • Adults: 2 gm once daily for only 3 days, taken preferably just before a meal
    • Children: 30 mg/kg once daily for only 3 days, taken preferably just before a meal
  • Hepatic Amoebiasis:
    • Adults: 1.50 gm/day in a single or divided doses, just before a meal, for 5 days
    • Children: 30 mg/kg/day, in a single or divided dose, just before a meal, for 5 days
  • Giardiasis:
    • Adults: 2 gm single dose, taken preferably just before a meal
    • Children: 35-50 mg/kg single dose, taken preferably just before a meal
  • Trichomoniasis:
    • Adults: 2 gm single dose, taken preferably just before a meal. The partner should also receive the same treatment concomitantly

Interaction

  • Not recommended with disulfiram
  • Close monitoring required if used simultaneously with warfarin

Contraindications

  • Hypersensitivity to imidazole derivatives

Side Effects

  • Most frequent side-effects: Gastrointestinal disturbances, nausea, epigastric pain, metallic taste, glossitis, stomatitis
  • Occasional side effects: Urticaria, moderate reversible leukopenia
  • Rare side-effects: Vertigo, ataxia, motor incoordination, paresthesia, peripheral neuropathy

Pregnancy & Lactation

Prescribed in pregnancy after the first trimester, not recommended during the first trimester or during lactation

Precautions & Warnings

  • Avoid alcohol during treatment
  • Avoid in patients with a history of blood dyscrasia

Therapeutic Class

  • Amoebicides
  • Anti-diarrhoeal
  • Antiprotozoal

Storage Conditions

Store in a cool, dry place, protected from heat

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