Jasochlor 250 mg (Tablet)
Unit Price: ৳ 1.21 (10 x 10: ৳ 121.00)
Strip Price: ৳ 12.10
Medicine Details
| Category | Details |
|---|---|
| Generic | Chloroquine phosphate |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of malaria
- Prophylaxis and suppression of malaria
- Treatment of amoebic hepatitis and abscess
- Treatment of discoid and systemic lupus erythematosus
- Treatment of rheumatoid arthritis
Composition
- Tablet: Each film coated tablet contains Chloroquine Phosphate BP 250 mg equiv. to approx. 150 mg of Chloroquine base
- Syrup: Each 5 mL contains Chloroquine Phosphate BP 80 mg equiv. to approx. 50 mg of Chloroquine base
Mode of Action
- Rapidly acting blood schizontocide with gametocytocidal activity
- Influences haemoglobin digestion by raising intravesicular pH
- Interferes with synthesis of nucleoproteins by the parasite
Dosage & Administration
- Doses expressed in terms of chloroquine base
- Treatment of acute malaria attack, clinical prophylaxis, hepatic amoebiasis, lupus erythematosus, rheumatoid arthritis, photoallergic reactions, and porphyria cutanea tarda
Interaction
- Interacts with neostigmine, pyridostigmine, antacids, kaolin, cimetidine, ranitidine, quinine, mefloquine, amodiaquine, artemisinin, metronidazole, ampicillin
Contraindications
- Known or suspected chloroquine resistance in P. falciparum
- Hypersensitivity
- Retinal damage
- Concurrent therapy with hepatotoxic drugs
Side Effects
- Gastro-intestinal symptoms
- Psychological symptoms
- Visual disturbances
- Haematological effects
- Alopecia, hair pigmentation changes
- Pigmentation of mucous membranes and skin
- Photosensitivity
- Auditory symptoms
- Nerve and muscle related symptoms
Pregnancy & Lactation
- Avoid use during pregnancy except for malaria treatment when benefits outweigh risks
- Consider potential adverse reactions in nursing infants
Precautions & Warnings
- Ocular examinations before and during treatment
- Caution in case of impaired liver or renal function, porphyria, psoriasis, or history of epilepsy
- Observation for haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase (G6PD) deficiency
Therapeutic Class
- Anti-malarial drugs
Storage Conditions
- Keep below 30°C temperature, away from light & moisture, and out of reach of children