Kanaquine 300 mg (Tablet)
Unit Price: ৳ 6.40 (10 x 10: ৳ 640.00)
Strip Price: ৳ 64.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Quinine sulfate |
| Company | Globe pharmaceuticals ltd |
| Also available as |
Indications
- Uncomplicated, severe and complicated falciparum malaria
- Falciparum malaria resistant to other drugs
- Prevention of nocturnal muscle cramps
- Alleviation of muscle cramps in Thomsen's disease
Pharmacology
Quinine is believed to interfere with protein metabolism and inhibits nucleic acid synthesis in malarial parasites. It is effective both as a suppressive drug and in the over clinical attack of malaria.
Dosage & Administration
- Adult:
- Oral: 600 mg every 8 hours for 7 days
- Parenteral: Loading dose of 20 mg/kg infused over 4 hours then maintenance dose of 10 mg/kg infused over 4 hours every 8-12 hours until patient can complete the 7 days course
- Children:
- Oral: 10 mg/kg every 8 hours for 7 days
- Parenteral: Dosage regimen calculated on a mg/kg basis
- Pregnancy: The adult treatment doses can safely be given to pregnant women
Contraindications
Hypersensitivity reaction, optic neuritis, black water fever
Side Effects
Cinchonism (tinnitus, headache, nausea, visual disturbances), hematological disorders, skin reaction
Pregnancy & Lactation
Considered safe in pregnancy when used in therapeutic dosage, excreted in breast milk in insignificant amounts
Precautions & Warnings
- Severe heart disease
- Myasthenia gravis
- Diabetes mellitus
- Slow IV injection
- Use of Mefloquine with Kanaquine sulphate may increase the chance of side effects
Therapeutic Class
Anti-malarial drugs
Storage Conditions
Use of Mefloquine with Kanaquine sulphate may increase the chance of side effects