Quin 300 mg (Tablet)

Unit Price: ৳ 3.47 (10 x 10: ৳ 347.00)
Strip Price: ৳ 34.70

Medicine Details

Category Details
Generic Quinine sulfate
Company Hudson pharmaceuticals ltd

Indications

  • Uncomplicated falciparum malaria
  • Severe falciparum malaria
  • Complicated falciparum malaria
  • Falciparum malaria resistant to other drugs
  • Prevention of nocturnal muscle cramps
  • Alleviation of muscle cramps in Thomsen's disease

Pharmacology

  • Interferes with protein metabolism
  • Inhibits nucleic acid synthesis in malarial parasites
  • Highly active blood schizonticide
  • Suppresses the asexual cycle of development of malaria parasites

Dosage & Administration

  • Adult:
    • Oral: 600 mg every 8 hours for 7 days
    • Parenteral: Loading dose of 20 mg/kg infused over 4 hours, then maintenance dose of 10 mg/kg every 8-12 hours
  • Children:
    • Oral: 10 mg/kg every 8 hours for 7 days
    • Parenteral: Dosage calculated on a mg/kg basis as for adult
  • Pregnancy: Treatment doses can be safely given to pregnant women

Contraindications

Hypersensitivity reaction, optic neuritis, black water fever

Side Effects

  • Cinchonism (tinnitus, headache, nausea, visual disturbances)
  • Hematological disorders
  • Skin reaction

Pregnancy & Lactation

Considered safe when used in therapeutic dosage in pregnancy, excreted in insignificant amount in breast milk

Precautions & Warnings

  • Severe heart disease
  • Myasthenia gravis
  • Diabetes mellitus
  • IV injection should be given slowly
  • Use of Mefloquine with Quin sulphate may increase the chance of side effects

Therapeutic Class

Anti-malarial drugs

Storage Conditions

Refer to specific storage instructions

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