Quin 300 mg (Tablet)
Unit Price: ৳ 3.47 (10 x 10: ৳ 347.00)
Strip Price: ৳ 34.70
Medicine Details
Category | Details |
---|---|
Generic | Quinine sulfate |
Company | Hudson pharmaceuticals ltd |
Indications
- Uncomplicated falciparum malaria
- Severe falciparum malaria
- Complicated falciparum malaria
- Falciparum malaria resistant to other drugs
- Prevention of nocturnal muscle cramps
- Alleviation of muscle cramps in Thomsen's disease
Pharmacology
- Interferes with protein metabolism
- Inhibits nucleic acid synthesis in malarial parasites
- Highly active blood schizonticide
- Suppresses the asexual cycle of development of malaria parasites
Dosage & Administration
- Adult:
- Oral: 600 mg every 8 hours for 7 days
- Parenteral: Loading dose of 20 mg/kg infused over 4 hours, then maintenance dose of 10 mg/kg every 8-12 hours
- Children:
- Oral: 10 mg/kg every 8 hours for 7 days
- Parenteral: Dosage calculated on a mg/kg basis as for adult
- Pregnancy: Treatment doses can be safely given to pregnant women
Contraindications
Hypersensitivity reaction, optic neuritis, black water fever
Side Effects
- Cinchonism (tinnitus, headache, nausea, visual disturbances)
- Hematological disorders
- Skin reaction
Pregnancy & Lactation
Considered safe when used in therapeutic dosage in pregnancy, excreted in insignificant amount in breast milk
Precautions & Warnings
- Severe heart disease
- Myasthenia gravis
- Diabetes mellitus
- IV injection should be given slowly
- Use of Mefloquine with Quin sulphate may increase the chance of side effects
Therapeutic Class
Anti-malarial drugs
Storage Conditions
Refer to specific storage instructions