Levosol 40 mg/5 ml (Syrup)

Indications

• Treatment of infections by gastrointestinal worm species such as roundworm, hookworm, pinworm, whipworm, and threadworm

Pharmacology

• Levamisole acts by paralysing susceptible intestinal worms and enhancing cellular immune responses in humans

Dosage & Administration

• Single administration after a light meal
• Dosage based on age groups with specific tablet or syrup quantities
• Additional dose for severe hookworm infection

Interaction

• May increase toxicity of phenytoin
• Increases bioavailability of ivermectin
• Decreases bioavailability of albendazole
• Alcohol causes disulfiram-like reaction

Contraindications

• No absolute contra-indication to the use of Levamisole

Side Effects

• Infrequent and mild side-effects include nausea, vomiting, abdominal pain, dizziness, headache, and encephalopathy-like syndrome

Pregnancy & Lactation

• Animal studies show no teratogenic effects, benefits weighed against possible dangers in pregnancy

Precautions & Warnings

• No evidence of sedation, mild and transient giddiness as infrequent side-effect
• No precautions suggested for driving or operating machinery
• Transient fever may occur in case of concurrent microfilaraemia

Overdose Effects

• Counter possible anticholinesterase activity with atropine
• Control blood pressure and respiration
• Avoid the use of sedatives

Therapeutic Class

• Anthelmintic

Storage Conditions

• Tablets to be stored in room temperature and protected from moisture
• Syrup to be stored in room temperature and protected from light

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