Mebantrin 100 mg/5 ml (Oral Suspension)
30 ml bottle: ৳ 15.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Mebendazole |
| Company | Pharmadesh laboratories ltd |
| Also available as |
Indications
- Treatment of threadworms
- Treatment of whipworms
- Treatment of roundworms
- Treatment of hookworms
Pharmacology
- Synthetic broad-spectrum anthelmintic
- Active against most nematodes and some other worms
- Inhibits formation of worms' microtubules
- Causes worms' glucose depletion
- 2-10% oral dose absorbed from GI tract
- Peak plasma concentration within 30 minutes to 7 hours
- Highly bound to plasma protein
- Elimination half-life of 2.8 to 9 hours
Dosage & Administration
- Adult dosage
- Child dosage over 2 years
- Single dose for threadworms
- Twice daily for 3 days for whipworms, roundworms, hookworms
- Possible second dose needed after 2 weeks if reinfection occurs
Interaction
- Preliminary evidence of cimetidine inhibiting Mebantrin metabolism
- Potential increase in plasma concentration
Contraindications
- Contraindicated in patients with known hypersensitivity to Mebendazole or any component of the formulation
Side Effects
- Transient symptoms of abdominal pain and diarrhea
- Expulsion of worms
- Rash
- Urticaria
- Angioedema
- Rare cases of convulsions
- Neutropenia
- Agranulocytosis
Pregnancy & Lactation
- Not recommended in pregnant women
- Unknown excretion in human milk
- Caution advised for nursing mothers
Precautions & Warnings
- Periodic assessment of organ system functions
- Informed consent for potential fetal risk in pregnant women
- Emphasis on cleanliness to prevent reinfection & transmission of infection
Use in Special Populations
- Limited study in children under two years
- Consideration of relative benefit/risk for treatment in children under two years
Overdose Effects
- Possible gastrointestinal complaints lasting up to a few hours
- Induction of vomiting and purging in case of accidental overdosage
Therapeutic Class
- Anthelmintic
Storage Conditions
- Cool and dry storage below 25°C
- Protection from light
- Keep out of reach of children