Mebendol 100 mg/5 ml (Oral Suspension)
30 ml bottle: ৳ 13.65
Medicine Details
Category | Details |
---|---|
Generic | Mebendazole |
Company | Doctors chemical works ltd |
Also available as |
Indications
- Treats threadworms
- Treats whipworms
- Treats roundworms
- Treats hookworms
Pharmacology
- Synthetic broad-spectrum anthelmintic
- Active against most nematodes and some other worms
- Inhibits formation of worms' microtubules
- Causes worms' glucose depletion
- 2-10% oral dose absorbed from GI tract
- Peak plasma concentration within 30 minutes to 7 hours
- Highly bound to plasma protein
- Elimination half-life is 2.8 to 9 hours
Dosage & Administration
- 100 mg for threadworms: Single dose
- 100 mg for whipworms, roundworms, hookworms: Twice daily for 3 days
- Second dose may be needed after 2 weeks if reinfection occurs
Interaction
- Cimetidine may inhibit Mebendol metabolism
Contraindications
- Hypersensitivity to Mebendazole or any component of the formulation
Side Effects
- Transient symptoms of abdominal pain and diarrhea
- Rash, urticaria, and angioedema
- Very rare cases of convulsions
- Neutropenia and agranulocytosis
Pregnancy & Lactation
- Not recommended in pregnant women
- Caution advised when administered to nursing mother
Precautions & Warnings
- Periodic assessment of organ system functions
- Warning for potential risk to the fetus in women taking Mebendol during pregnancy
- Cleanliness is important to prevent reinfection & transmission of the infection
Use in Special Populations
- Not extensively studied in children under two years
- Relative benefit/risk should be considered in children under two years
Overdose Effects
- Gastrointestinal complaints lasting up to a few hours
- Vomiting and purging should be induced in case of accidental overdosage
Therapeutic Class
- Anthelmintic
Storage Conditions
- Store in a cool and dry place below 25°C
- Protected from light
- Keep out of the reach of children
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