Mebendol 100 mg/5 ml (Oral Suspension)

30 ml bottle: ৳ 13.65

Medicine Details

Indications

  • Treats threadworms
  • Treats whipworms
  • Treats roundworms
  • Treats hookworms

Pharmacology

  • Synthetic broad-spectrum anthelmintic
  • Active against most nematodes and some other worms
  • Inhibits formation of worms' microtubules
  • Causes worms' glucose depletion
  • 2-10% oral dose absorbed from GI tract
  • Peak plasma concentration within 30 minutes to 7 hours
  • Highly bound to plasma protein
  • Elimination half-life is 2.8 to 9 hours

Dosage & Administration

  • 100 mg for threadworms: Single dose
  • 100 mg for whipworms, roundworms, hookworms: Twice daily for 3 days
  • Second dose may be needed after 2 weeks if reinfection occurs

Interaction

  • Cimetidine may inhibit Mebendol metabolism

Contraindications

  • Hypersensitivity to Mebendazole or any component of the formulation

Side Effects

  • Transient symptoms of abdominal pain and diarrhea
  • Rash, urticaria, and angioedema
  • Very rare cases of convulsions
  • Neutropenia and agranulocytosis

Pregnancy & Lactation

  • Not recommended in pregnant women
  • Caution advised when administered to nursing mother

Precautions & Warnings

  • Periodic assessment of organ system functions
  • Warning for potential risk to the fetus in women taking Mebendol during pregnancy
  • Cleanliness is important to prevent reinfection & transmission of the infection

Use in Special Populations

  • Not extensively studied in children under two years
  • Relative benefit/risk should be considered in children under two years

Overdose Effects

  • Gastrointestinal complaints lasting up to a few hours
  • Vomiting and purging should be induced in case of accidental overdosage

Therapeutic Class

  • Anthelmintic

Storage Conditions

  • Store in a cool and dry place below 25°C
  • Protected from light
  • Keep out of the reach of children

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