Albezole 400 mg (Chewable Tablet)
Unit Price: ৳ 3.80 (40's pack: ৳ 152.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Apollo pharmaceutical ltd |
Indications
- Hookworm infestation
- Roundworm infestation
- Threadworm infestation
- Whipworm infestation
- Strongyloides infestation
- Tapeworm infestation
- Opisthorchi infestation
- Hydatid infestation
Description
- Benzimidazole anthelmintic
- Active against nematodes and cestodes
- Vermicidal, ovicidal, larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Depletes energy level in helminths
- Exerts anthelmintic effect by immobilization of parasite
- Extensively metabolized, probably in the liver
- Poorly absorbed from the gastrointestinal tract
- Rapid extensive first-pass metabolism
Dosage & Administration
- Recommended dosage for adults and children over 2 years
- Recommended dosage for children of 1-2 years
- Not recommended for children under 1 year
- Dosing regimen for Hydatid disease (Echinococcosis)
- Dosing regimen for cystic echinococcosis
- Dosing regimen for alveolar echinococcosis
- Dosing regimen in giardiasis
Interaction
- No reported pharmacodynamic interaction
- No reported pharmacokinetic interaction
Contraindications
- Not normally used in neonates
- Possible dose reduction in children weighing less than 10 kg
- Should not be given during pregnancy or to women thought to be pregnant
- No evidence to suggest alteration of dose in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia (rare)
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- US FDA Pregnancy category C
- Avoided in pregnancy and lactation unless potential benefits outweigh possible risks to the fetus
Precautions & Warnings
- Blood counts and liver function tests before treatment and during each cycle
- Considerations for breastfeeding
- Exclusion of pregnancy before starting treatment
- Continuous medical supervision with regular monitoring for Echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children