Depol Extended 665 mg (Tablet (Extended Release))
Unit Price: ৳ 2.00 (12 x 10: ৳ 240.00)
Strip Price: ৳ 20.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol |
| Company | Desh pharmaceuticals ltd |
Title
- Depol Extended 665 mg Tablet
Categories
- Medicine
- Health
- Pharmaceutical
Description
- Depol Extended is indicated for fever, common cold and influenza, headache, toothache, earache, bodyache, myalgia, neuralgia, dysmenorrhoea, sprains, colic pain, back pain, post-operative pain, postpartum pain, inflammatory pain and post vaccination pain in children. It is also indicated for rheumatic & osteoarthritic pain and stiffness of joints.
- Depol Extended 665 mg XR Tablet is a medication that performs its action by obstructing the release of pain and fever chemical messengers.
- Depol Extended 665 mg XR Tablet is used for the treatment and prevention of conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps and fever.
Dosage
- Adult: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily.
- Children (6-12 years): ½ to 1 tablet 3 to 4 times daily. For long term treatment it is wise not to exceed the dose beyond 2.6 gm/day.
- Adults & Children over 12 years: Two tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). The tablet must not be crushed.
- Children under 3 months: 10 mg/kg body weight.
Mode of Action
- Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity.
- Paracetamol is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis.
Interaction
- Patients who have taken barbiturates, tricyclic antidepressants and alcohol may show diminished ability to metabolize large doses of Depol Extended. Alcohol can increase the hepatotoxicity of Depol Extended overdosage.
- Chronic ingestion of anticonvulsants or oral steroid contraceptives may prevent attainment of therapeutic Depol Extended levels by increasing first-pass metabolism or clearance.
Contraindications
- Known hypersensitivity to Paracetamol.
Side Effects
- Side effects of Depol Extended are usually mild, though haematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been reported.
- Pancreatitis, skin rashes, and other allergic reactions occur occasionally.
Pregnancy & Lactation
- Epidemiological studies in human pregnancy have shown no ill effects due to Paracetamol used in the recommended dosage, but patients should follow the advice of their doctor regarding its use.
- Paracetamol is excreted in breast milk, but not in a clinically significant amount.
Precautions & Warnings
- Care is advised in the administration of Depol Extended to patients with severe renal or severe hepatic impairment.
- Do not exceed the stated dose.
- Patients should be advised not to take other Depol Extended-containing products concurrently.
Overdose Effects
- Liver damage is possible in adults who have taken 10 g or more of Depol Extended.
- Ingestion of 5 g or more of Depol Extended may lead to liver damage if the patient has following risk factors: If the patient is on long term treatment with Carbamazepine, Phenobarbitone, Phenytoin, Primidone, Rifampicin, St John’s Wort or other drugs that induce liver enzymes, or regularly consumes Ethanol in excess of recommended amounts, or is likely to be Glutathione deplete e.g. eating disorders, cystic fibrosis, HIV infection, starvation, cachexia.
Therapeutic Class
- Non opioid analgesics
Storage Conditions
- Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C8H9NO2
Commonly Asked Questions
- What is Depol Extended 665 mg XR Tablet?
- What are the uses of Depol Extended 665 mg XR Tablet?
- What are the Side Effects of Depol Extended 665 mg XR Tablet Depol Extended 665 mg XR Tablet?
- What are the instructions for storage and disposal of Depol Extended 665 mg XR Tablet?
- Should I use Depol Extended 665 mg XR Tablet empty stomach, before food or after food?
- How long do I need to use Depol Extended 665 mg XR Tablet before I see improvement in my conditions?
- Is there any food or drink I need to avoid while taking Depol Extended 665 mg XR Tablet?
- Will Depol Extended 665 mg XR Tablet be more effective if taken in more than the recommended dose?
- Can I take other medications along with Depol Extended 665 mg XR Tablet?
- Can I take Depol Extended 665 mg XR Tablet with antibiotics?
- Is Depol Extended 665 mg XR Tablet an NSAID drug?