Longpara 665 mg (Tablet (Extended Release))

Unit Price: ৳ 2.00 (20 x 10: ৳ 400.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Paracetamol
Company Ibn sina pharmaceuticals ltd
Also available as
Sinapol 500 mg tablet

Indications

  • Fever
  • Common cold
  • Influenza
  • Headache
  • Toothache
  • Earache
  • Bodyache
  • Myalgia
  • Neuralgia
  • Dysmenorrhoea
  • Sprains
  • Colic pain
  • Back pain
  • Post-operative pain
  • Postpartum pain
  • Inflammatory pain
  • Post vaccination pain in children
  • Rheumatic pain
  • Osteoarthritic pain
  • Stiffness of joints

Pharmacology

  • Analgesic properties
  • Antipyretic properties
  • Weak anti-inflammatory activity
  • Acts in the central nervous system (CNS)
  • Increases the pain threshold
  • Inhibits cyclooxygenase (COX) enzymes
  • Prostaglandin (PG) synthesis inhibition
  • Para aminophenol derivative

Dosage & Administration

  • Tablet:
    • Adult dosage: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily
    • Children (6-12 years) dosage: ½ to 1 tablet 3 to 4 times daily
  • Extended Release Tablet:
    • Adults & Children over 12 years dosage: Two tablets every 6 to 8 hours (maximum of 6 tablets in any 24 hours)
  • Syrup/Suspension:
    • Dosage for Children under 3 months, 3 months to below 1 year, 1-5 years, 6-12 years, and Adults
  • Suppository:
    • Dosage for Children 3-12 months, 1-5 years, 6-12 years, Adults & children over 12 years
  • Paediatric Drop:
    • Dosage for Children up to 3 months, 4 to 11 months, 7 to 2 years
  • Paracetamol tablet with actizorb technology:
    • Adults and children (aged 12 years and over) dosage
    • Children (7 to 11 years) dosage

Interaction

  • Diminished ability to metabolize large doses with barbiturates, tricyclic antidepressants, and alcohol
  • Increased hepatotoxicity in case of Longpara overdosage with alcohol
  • Chronic ingestion of anticonvulsants or oral steroid contraceptives may prevent attainment of therapeutic Longpara levels

Contraindications

  • Known hypersensitivity to Paracetamol

Side Effects

  • Mild side effects
  • Haematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis
  • Pancreatitis
  • Skin rashes
  • Other allergic reactions

Pregnancy & Lactation

  • Epidemiological studies show no ill effects in human pregnancy
  • Excretion in breast milk in not a clinically significant amount

Precautions & Warnings

  • Care in administration to patients with severe renal or severe hepatic impairment
  • Hazard of overdose is greater in non-cirrhotic alcoholic liver disease patients
  • Advised not to exceed the stated dose
  • Not to be taken concurrently with other Longpara-containing products
  • Use only when clearly necessary

Overdose Effects

  • Possible liver damage in adults who have taken 10 g or more of Longpara
  • Liver damage risk in ingestion of 5 g or more with certain risk factors
  • Symptoms of Longpara overdose
  • Immediate treatment essential
  • Plasma Longpara concentration measurement
  • Treatment with activated charcoal and N-acetylcysteine

Therapeutic Class

  • Non opioid analgesics

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C8H9NO2
  • Chemical Structure Image: https://medex.com.bd/storage/res/g-res-860-paracetamol-chemical-structure-JLKHDuG7hxR2MserFZ27.svg

Common Questions about Longpara 665 mg Tablet

  • Medication action by obstructing release of pain and fever chemical messengers
  • Uses for treatment and prevention of conditions and symptoms of diseases like Post immunization pyrexia, menstrual cramps, and fever
  • Possible side effects including allergic reaction, gastric ulcers, fatigue, anemia, nausea, and vomiting
  • Instructions for storage and disposal
  • Advice for taking with food or milk to prevent upset stomach

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