Napa 250 mg (Suppository)
Unit Price: ৳ 5.00 (4 x 5: ৳ 100.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Indications
- Fever
- Common cold and influenza
- Headache
- Toothache
- Earache
- Bodyache
- Myalgia
- Neuralgia
- Dysmenorrhoea
- Sprains
- Colic pain
- Back pain
- Post-operative pain
- Postpartum pain
- Inflammatory pain
- Post vaccination pain in children
- Rheumatic and osteoarthritic pain
- Stiffness of joints
Pharmacology
- Analgesic properties
- Antipyretic properties
- Weak anti-inflammatory activity
- Action in the CNS
- Inhibition of cyclooxygenase (COX-1, COX-2, COX-3) enzymes
- Increase in pain threshold
- Prostaglandin synthesis inhibition
- Para-aminophenol derivative
Dosage & Administration
- Tablet for adults
- Tablet for children (6-12 years)
- Extended release tablet for adults and children over 12 years
- Syrup/suspension for children under 3 months
- Syrup/suspension for 3 months to below 1 year
- Syrup/suspension for 1-5 years
- Syrup/suspension for 6-12 years
- Syrup/suspension for adults
- Suppository for children (3-12 months)
- Suppository for children (1-5 years)
- Suppository for children (6-12 years)
- Suppository for adults and children over 12 years
- Pediatric drop for children up to 3 months
- Pediatric drop for 4 to 11 months
- Pediatric drop for 7 to 12 years
- Paracetamol tablet with actizorb technology for adults and children (aged 12 years and over)
Interaction
- Diminished ability to metabolize large doses with barbiturates
- Diminished ability to metabolize large doses with tricyclic antidepressants
- Diminished ability to metabolize large doses with alcohol
- Increased hepatotoxicity of overdosage with alcohol
- Chronic ingestion effects of anticonvulsants
- Chronic ingestion effects of oral steroid contraceptives
Contraindications
- Known hypersensitivity to Paracetamol
Side Effects
- Mild side effects
- Haematological reactions including thrombocytopenia
- Haematological reactions including leucopenia
- Haematological reactions including pancytopenia
- Haematological reactions including neutropenia
- Haematological reactions including agranulocytosis
- Pancreatitis
- Skin rashes
- Other allergic reactions
Pregnancy & Lactation
- Epidemiological studies show no ill effects in human pregnancy
- Advice to follow doctor's guidance during pregnancy
- Excretion in breast milk
Precautions & Warnings
- Care advised for severe renal impairment
- Care advised for severe hepatic impairment
- Hazard of overdose is greater in non-cirrhotic alcoholic liver disease
- Advice not to exceed the stated dose
- Advice not to take other Napa-containing products concurrently
Overdose Effects
- Possible liver damage in adults with 10 g or more intake
- Liver damage with 5 g or more intake under certain risk factors
- Symptoms of overdose in the first 24 hours
- Liver damage becoming apparent 12 to 48 hours after ingestion
- Abnormalities of glucose metabolism
- Metabolic acidosis
- Hepatic failure leading to encephalopathy, haemorrhage, hypoglycaemia, cerebral oedema, and death
- Acute renal failure with acute tubular necrosis
- Immediate treatment essential
- Treatment with activated charcoal within 1 hour of ingestion
- Measurement of plasma Napa concentration at 4 hours or later after ingestion
- Treatment with N-acetylcysteine within 24 hours after ingestion
- Maximum protective effect within 8 hours post-ingestion
- Intravenous N-acetylcysteine for serious hepatic dysfunction
Therapeutic Class
- Non-opioid analgesics
Storage Conditions
- Keep in dry place
- Keep away from light
- Keep away from heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H9NO2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-860-paracetamol-chemical-structure-JLKHDuG7hxR2MserFZ27.svg
Common Questions about Napa 250 mg Suppository
- Action by obstructing the release of pain and fever chemical messengers
- Uses for post immunization pyrexia, menstrual cramps, and fever
- Possible side effects including allergic reaction, gastric ulcers, fatigue, anemia, nausea, and vomiting
- Instructions for storage and disposal
- Recommendation to take with food or milk
- Duration of use until complete eradication of the disease
- Absence of food or drink restrictions
- No need to take more than recommended doses
- Consultation required before taking with other medications
- Non-classification as NSAID drug