Zerin 120 mg/5 ml (Oral Suspension)
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Product Title
Zerin 120 mg/5 ml Suspension
Category
Medicine
Indications
- Fever
- Common cold
- Influenza
- Headache
- Toothache
- Earache
- Bodyache
- Myalgia
- Neuralgia
- Dysmenorrhoea
- Sprains
- Colic pain
- Back pain
- Post-operative pain
- Postpartum pain
- Inflammatory pain
- Post vaccination pain
Pharmacology
Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. It is thought to act primarily in the CNS, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase (COX-1, COX-2) and COX-3 enzymes involved in prostaglandin (PG) synthesis.
Dosage & Administration
- Tablet:
- Adult: 1-2 tablets every 4 to 6 hours up to a maximum of 4 gm (8 tablets) daily
- Children (6-12 years): ½ to 1 tablet 3 to 4 times daily
- Extended Release Tablet: Two tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours)
- Syrup/Suspension:
- Children under 3 months: 10 mg/kg body weight 3 to 4 times daily
- 3 months to below 1 year: ½ to 1 teaspoonful 3 to 4 times daily
- 1-5 years: 1 -2 teaspoonful 3 to 4 times daily
- 6-12 years: 2-A teaspoonful 3 to 4 times daily
- Adults: 4-8 teaspoonful 3 to 4 times daily
Interaction
Patients who have taken barbiturates, tricyclic antidepressants, and alcohol may show diminished ability to metabolize large doses of Zerin. Alcohol can increase the hepatotoxicity of Zerin overdosage.
Contraindications
Known hypersensitivity to Paracetamol
Side Effects
- Mild side effects
- Haematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis
- Pancreatitis
- Skin rashes
- Other allergic reactions
Pregnancy & Lactation
Epidemiological studies in human pregnancy have shown no ill effects due to Paracetamol used in the recommended dosage. Paracetamol is excreted in breast milk, but not in a clinically significant amount. Available published data do not contraindicate breastfeeding.
Precautions & Warnings
Care is advised in the administration of Zerin to patients with severe renal or severe hepatic impairment. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease.
Overdose Effects
- Liver Damage Symptoms:
- Pallor
- Nausea
- Vomiting
- Anorexia
- Abdominal pain
- Management: Immediate treatment is essential in the management of Zerin overdose. Treatment with activated charcoal should be considered if the overdose has been taken within 1 hour. Plasma Zerin concentration should be measured at 4 hours or later after ingestion. Treatment with N-acetylcysteine may be used up to 24 hours after ingestion of Zerin.
Therapeutic Class
Non opioid analgesics
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Chemical Structure
- Molecular Formula: C8H9NO2
- Chemical Structure Image: https://medex.com.bd/storage/res/g-res-860-paracetamol-chemical-structure-JLKHDuG7hxR2MserFZ27.svg
Commonly Asked Questions
- What is Zerin 120 mg/5 ml Suspension?
- What are the uses of Zerin 120 mg/5 ml Suspension?
- What are the Side Effects of Zerin 120 mg/5 ml Suspension?
- What are the instructions for storage and disposal Zerin 120 mg/5 ml Suspension?
- Should I use Zerin 120 mg/5 ml Suspension empty stomach, before food or after food?
- How long do I need to use Zerin 120 mg/5 ml Suspension before I see improvement in my conditions?
- Is there any food or drink I need to avoid while taking Zerin 120 mg/5 ml Suspension?
- Will Zerin 120 mg/5 ml Suspension be more effective if taken in more than the recommended dose?
- Can I take other medications along with Zerin 120 mg/5 ml Suspension?
- Can I take Zerin 120 mg/5 ml Suspension with antibiotics?
- Is Zerin 120 mg/5 ml Suspension an NSAID drug?
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