Bepol Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 1.50 (100's pack: ৳ 150.00)

Medicine Details

Category	Details
Generic	Paracetamol caffeine
Company	Bengal drugs ltd

Indications

Headache
Migraine
Toothache
Neuralgia
Feverishness
Period pain
Sore throat
Backache
Help to reduce the temperature
Aches and pain of colds and flu

Pharmacology

Combination of Paracetamol and Caffeine
Analgesic and antipyretic properties
Weak anti-inflammatory activity
Caffeine increases solubility and transmembrane permeation of Paracetamol
Increases pain threshold and tolerance of pain
Raises vessel tone in the brain

Dosage & Administration

Adult dose: 1-2 tablets every 4-6 hours
Maximum dose: 8 tablets daily
Not recommended for children below 12 years

Interaction

May reduce serum levels with anticonvulsants
May enhance anticoagulant effect of warfarin
Accelerated absorption with metoclopramide and domperidone
May increase serum levels with probenecid
May reduce absorption with colestyramine
May cause severe hypothermia with phenothiazine

Contraindications

Severe renal function impairment
Hepatic disease (Viral Hepatitis)
Known hypersensitivity to paracetamol or caffeine

Side Effects

Mild side effects
Haematological reactions
Thrombocytopenia
Leukopenia
Pancytopenia
Neutropenia
Agranulocytosis
Pancreatitis
Skin rashes
Allergic reactions

Pregnancy & Lactation

Consultation required for pregnant mothers
Can be taken while breastfeeding

Precautions & Warnings

Given cautiously in hepatic or renal failure
Caution in patients taking other hepatotoxic medication
Prolonged use without consulting a physician to be avoided

Overdose Effects

Symptoms of overdose in the first 24 hours
Liver damage may occur 12 to 40 hours after ingestion
Abnormalities of glucose metabolism and metabolic acidosis may occur

Therapeutic Class

Non opioid analgesics

Storage Conditions

Store in a cool and dry place
Protect from light and moisture
Keep out of the reach of children

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