Cafceta 500 mg+65 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Paracetamol caffeine |
Company | Peoples pharma ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
Paracetamol and Caffeine combination. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine is an alkaloid which is a theophylline-like xanthine derivative. By intermolecular association with Paracetamol, Caffeine increases the solubility and transmembrane permeation of Paracetamol. Caffeine increases the pain threshold and tolerance of pain.
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.
- Child dose: Not recommended for children below 12 years.
Interaction
May reduce serum levels with anticonvulsants, enhance the anticoagulant effect of warfarin, accelerate absorption with metoclopramide and domperidone, increase serum levels with probenecid, of chloramphenicol, reduce absorption with colestyramine, and cause severe hypothermia with phenothiazine.
Contraindications
Severe renal function impairment, hepatic disease (Viral Hepatitis), and known hypersensitivity to paracetamol or caffeine.
Side Effects
Mild side effects, though haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.
Pregnancy & Lactation
Pregnant mothers should consult with doctors before taking Paracetamol & Caffeine. Can be taken whilst breast feeding.
Precautions & Warnings
Given cautiously in patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use without consulting a physician should be avoided.
Overdose Effects
Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia, abdominal pain, liver damage, abnormalities of glucose metabolism, and metabolic acidosis.
Therapeutic Class
- Non opioid analgesics
Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of children.