Duet 500 mg+65 mg (Tablet)
Medicine Details
Category | Details |
---|---|
Generic | Paracetamol caffeine |
Company | Silva pharmaceuticals ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
Combination of Paracetamol and Caffeine with analgesic, antipyretic, weak anti-inflammatory properties and increased pain threshold and tolerance of pain.
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily
- Child dose: Not recommended for children below 12 years
Interaction
May reduce serum levels with anticonvulsants, enhance the anticoagulant effect of warfarin, accelerate absorption with metoclopramide, increase serum levels with probenecid, increase serum levels of chloramphenicol, reduce absorption with colestyramine, and cause severe hypothermia with phenothiazine.
Contraindications
Severe renal function impairment, hepatic disease (Viral Hepatitis), known hypersensitivity to paracetamol or caffeine.
Side Effects
Mild side effects include haematological reactions, thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis, pancreatitis, skin rashes, and other allergic reactions.
Pregnancy & Lactation
Consultation required for pregnant mothers. Can be taken while breastfeeding.
Precautions & Warnings
Use cautiously in patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use without consulting a physician should be avoided.
Overdose Effects
Symptoms of Paracetamol overdose include pallor, nausea, vomiting, anorexia, abdominal pain, liver damage apparent 12 to 40 hours after ingestion, and abnormalities of glucose metabolism and metabolic acidosis.
Therapeutic Class
Non-opioid analgesics
Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of children.
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