Nova Plus 500 mg+65 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Cosmic pharma ltd |
Indications
- Headache
- Migraine
- Toothache
- Neuralgia
- Feverishness
- Period pain
- Sore throat
- Backache
- Help to reduce the temperature
- Aches and pain of colds and flu
Pharmacology
Combination of Paracetamol and Caffeine. Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity. Caffeine increases the solubility and transmembrane permeation of Paracetamol and increases the pain threshold and tolerance of pain.
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.
- Child dose: Not recommended for children below 12 years.
Interaction
May reduce serum levels with anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin with prolonged use. Accelerated absorption with metoclopramide and domperidone. May increase serum levels with probenecid. May increase serum levels of chloramphenicol. May reduce absorption with colestyramine within 1 hr of admin. May cause severe hypothermia with phenothiazine.
Contraindications
Contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Known hypersensitivity to paracetamol or caffeine.
Side Effects
Haematological reactions, pancreatitis, skin rashes, allergic reactions.
Pregnancy & Lactation
Pregnant mothers should consult with doctors before taking Paracetamol & Caffeine. Can be taken whilst breastfeeding.
Precautions & Warnings
Given cautiously in patients with hepatic or renal failure, in patients taking other hepatotoxic medication. Prolonged use without consulting a physician should be avoided.
Overdose Effects
Symptoms of Paracetamol overdose in the first 24 hours are pallor, nausea, vomiting, anorexia and abdominal pain. Liver damage may become apparent 12 to 40 hours after ingestion. Abnormalities of glucose metabolism and metabolic acidosis may occur.
Therapeutic Class
Non opioid analgesics
Storage Conditions
Store in a cool and dry place, protect from light and moisture. Keep all medicines out of the reach of children.