Para Caf 500 mg+65 mg (Tablet)
Unit Price: ৳ 1.90 (100's pack: ৳ 190.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Paracetamol caffeine |
| Company | Seema pharmaceuticals ltd |
Title, Categories, and Description
- Headache relief medicine
- Non-Opioid Analgesic
- Combination of Paracetamol and Caffeine
- Analgesic and Antipyretic Properties
- Alkaloid-based treatment
- Indicated for Headache, Migraine, Toothache, Neuralgia, Feverishness, Period Pain, Sore Throat, Backache
- Helps to reduce temperature
- Aches and pain relief for colds and flu
Dosage & Administration
- Adult dose: 1-2 tablets every 4-6 hours
- Maximum adult dose: 8 tablets daily
- Not recommended for children below 12 years
Pharmacology
- Intermolecular association of Caffeine with Paracetamol
- Increases solubility and transmembrane permeation of Paracetamol
- Increases pain threshold and tolerance
- Raises vessel tone in the brain
Interaction
- May reduce serum levels with anticonvulsants
- Enhances anticoagulant effect of warfarin and other coumarins
- Accelerated absorption with metoclopramide and domperidone
- May increase serum levels with probenecid
- May reduce absorption with colestyramine within 1 hr of admin
- May cause severe hypothermia with phenothiazine
Contraindications
- Severe renal function impairment
- Hepatic disease (Viral Hepatitis)
- Known hypersensitivity to paracetamol or caffeine
Side Effects
- Mild side effects usually
- Haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis
- Pancreatitis, skin rashes, and other allergic reactions occasionally
Pregnancy & Lactation
- Consultation required for pregnant mothers
- Safe for breastfeeding mothers
Precautions & Warnings
- Cautious use in hepatic or renal failure patients
- Cautious use with other hepatotoxic medication
- Avoid prolonged use without consulting a physician
Overdose Effects
- Symptoms in the first 24 hours: pallor, nausea, vomiting, anorexia, abdominal pain
- Liver damage may appear 12-40 hours after ingestion
- Abnormalities of glucose metabolism and metabolic acidosis
Therapeutic Class
- Paracetamol and Caffeine Combination
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children