Pol Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)

Strip Price: ৳ 25.00

Medicine Details

Category	Details
Generic	Paracetamol caffeine
Company	Globe pharmaceuticals ltd

Indications

Headache
Migraine
Toothache
Neuralgia
Feverishness
Period pain
Sore throat
Backache
Help to reduce the temperature
Aches and pain of colds and flu

Pharmacology

Combination of Paracetamol and Caffeine. Paracetamol has analgesic, antipyretic properties, weak anti-inflammatory activity. Caffeine increases solubility and transmembrane permeation of Paracetamol, raises pain threshold, tolerance of pain, and vessel tone in the brain.

Dosage & Administration

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.
Child dose: Not recommended for children below 12 years.

Interaction

May reduce serum levels with anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine)
May enhance anticoagulant effect of warfarin and other coumarins with prolonged use
Accelerated absorption with metoclopramide and domperidone
May increase serum levels with probenecid
May increase serum levels of chloramphenicol
May reduce absorption with colestyramine within 1 hr of admin
May cause severe hypothermia with phenothiazine

Contraindications

Severe renal function impairment, hepatic disease (Viral Hepatitis), hypersensitivity to paracetamol or caffeine

Side Effects

Mild side effects with haematological reactions, thrombocytopenia, leukopenia, pancytopenia, neutropenia, agranulocytosis, pancreatitis, skin rashes, allergic reactions

Pregnancy & Lactation

Consult doctors before taking while pregnant. Can be taken during breastfeeding

Precautions & Warnings

Cautious use in hepatic or renal failure, with other hepatotoxic medication, avoid prolonged use without consulting a physician

Overdose Effects

Symptoms: pallor, nausea, vomiting, anorexia, abdominal pain. Liver damage may become apparent 12 to 40 hours after ingestion. Abnormalities of glucose metabolism, metabolic acidosis may occur

Therapeutic Class

Non opioid analgesics

Storage Conditions

Store in a cool, dry place, protect from light and moisture. Keep out of reach of children.