Tamino Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)
Strip Price: ৳ 25.00

Medicine Details

Category Details
Generic Paracetamol caffeine
Company Nipro jmi pharma ltd

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Help to reduce the temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Paracetamol has analgesic and antipyretic properties with weak anti-inflammatory activity
  • Caffeine is an alkaloid with theophylline-like xanthine derivative
  • Caffeine increases the solubility and transmembrane permeation of Paracetamol
  • Caffeine increases pain threshold and tolerance of pain
  • Caffeine raises vessel tone in the brain

Dosage & Administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Maximum adult dose: 8 tablets daily
  • Not recommended for children below 12 years

Interaction

  • May reduce serum levels with anticonvulsants
  • May enhance anticoagulant effect of warfarin with prolonged use
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine within 1 hr of admin
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Severe renal function impairment
  • Hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side Effects

  • Mild side effects of paracetamol
  • Haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis
  • Pancreatitis, skin rashes, and other allergic reactions

Pregnancy & Lactation

  • Pregnant mothers should consult with doctors before taking
  • Can be taken whilst breastfeeding

Precautions & Warnings

  • Given cautiously in patients with hepatic or renal failure
  • In patients taking other hepatotoxic medication
  • Prolonged use without consulting a physician should be avoided

Overdose Effects

  • Symptoms of Paracetamol overdose in the first 24 hours
  • Liver damage may become apparent 12 to 40 hours after ingestion
  • Abnormalities of glucose metabolism and metabolic acidosis

Therapeutic Class

  • Non opioid analgesics

Storage Conditions

  • Store in a cool and dry place
  • Protect from light and moisture
  • Keep all medicines out of the reach of children

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