Atezen 50 mg (Tablet)
Unit Price: ৳ 0.77 (10 x 10: ৳ 77.00)
Strip Price: ৳ 7.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Atenolol |
| Company | Zenith pharmaceuticals ltd |
| Also available as |
Indications
- Management of hypertension
- Long-term management of angina pectoris
- Management of acute myocardial infarction
Pharmacology
- Beta-1 selective (cardioselective) beta-adrenergic receptor antagonist
- Hydrophilic nature
Dosage & Administration
- Initial dose of 50mg for hypertension
- Initial dose of 50mg for angina pectoris
- Intravenous doses for acute myocardial infarction
Interactions
- Additive effect with catecholamine-depleting drugs
- Additive effect with calcium channel blockers
- Potent negative inotropic and chronotropic effects with disopyramide
- Additive properties with amiodarone
- Exacerbation of rebound hypertension with clonidine withdrawal
- Decreased hypotensive effects with prostaglandin synthase inhibiting drugs
Contraindications
- Sinus bradycardia
- Greater than first degree heart block
- Cardiogenic shock
- Overt cardiac failure
- Hypersensitivity to atenolol or its components
Side Effects
- Agranulocytosis
- Allergic reactions
- Central Nervous System effects
- Gastrointestinal effects
- Skin rashes
- Erythematous rash
Pregnancy & Lactation
- Pregnancy Category D
- Caution in nursing women
- Likelihood of bradycardia in breast-fed infants
Precautions & Warnings
- Evaluation of patients already on beta blockers
- Adjustment for impaired renal function
- Dose selection for elderly patients
- Assessment of renal function in hypertension or myocardial infarction
Use in Special Populations
- Dosage adjustment for elderly and renal impaired patients
- Maximum dosages recommended based on creatinine clearance
Overdose Effects
- Symptoms of lethargy, respiratory disorder, bradycardia
- Possible congestive heart failure, hypotension, bronchospasm, hypoglycemia
- Treatment involving induced emesis, gastric lavage, activated charcoal, hemodialysis, intensive support care
Therapeutic Class
- Beta-adrenoceptor blocking drugs
- Beta-blockers
Storage Conditions
- Expiry date adherence
- Protection from children
- Dispensation only on registered physician's prescription